Cell Based Assays
Invitrogen™ eBioscience™ Calcein Violet 450 AM Viability Dye
Membrane-permeable live-cell labeling dye. Upon entering the cell, intracellular esterases cleave the acetoxymethyl (AM) ester group, yielding the membrane-impermeable Calcein Violet fluorescent dye. Apoptotic and dead cells with compromised cell membranes do not retain Calcein Violet 450.
Invitrogen™ eBioscience™ Calcein Blue AM Viability Dye
Membrane-permeable live-cell labeling dye. Upon entering the cell, intracellular esterases cleave the acetoxymethyl (AM) ester group, yielding the membrane-impermeable Calcein Blue fluorescent dye. Apoptotic and dead cells with compromised cell membranes do not retain Calcein Blue.
Invitrogen™ eBioscience™ Indo-1 AM Calcium Sensor Dye
Membrane-permeable dye used to determine changes in calcium concentrations in the cell using fluorescence microscopy, flow cytometry, fluorescence spectroscopy and fluorescence microplate readers. Once Indo-1 enters the cell, esterases cleave the AM group yielding a membrane-impermeable dye.
Invitrogen™ eBioscience™ Fura-2 AM Dye
Imaging dye that binds to free Ca2+. Fura-2 is the preferred dye for ratiometric imaging microscopy with digital image analysis, especially when altering excitation wavelengths is more practical than detecting multiple emission wavelengths.
Invitrogen™ eBioscience™ Calcium Sensor Dye eFluor™ 514
Membrane-permeable dye used to monitor changes in intracellular free calcium concentrations in the cell. Once eFluor™ 514 Calcium Sensor Dye enters the cell, cellular esterases cleave the AM group yielding a membrane-impermeable dye fluorescing at ≈520nm.
Invitrogen™ eBioscience™ Fixable Viability Dye eFluor™ 450
A viability dye that can be used to irreversibly label dead cells prior to cryopreservation, fixation, and/or permeabilization procedures.
Invitrogen™ eBioscience™ Fixable Viability Dye eFluor™ 660
Can be used to irreversibly label dead cells prior to cryopreservation, fixation and/or permeabilization procedures. Unlike 7-AAD and PI, cells labeled with Fixable Viability Dyes can be washed, fixed, permabilized and stained for intracellular antigens without loss of staining intensity.
Invitrogen™ eBioscience™ Fixable Viability Dye eFluor™ 780
A viability dye that can be used to irreversibly label dead cells prior to cryopreservation, fixation, and/or permeabilization procedures.
Invitrogen™ eBioscience™ DRAQ5™
Anthraquinone dye with high affinity for double-stranded DNA. It is a membrane-permeable dye that can label live or fixed/dead cells.
Thermo Scientific Chemicals Vinblastine Sulfate, 98%
CAS: 143-67-9 Formule moléculaire: C46H60N4O13S Synonyme: Vincaleukblastine sulfate
Thermo Scientific Chemicals Temsirolimus, 99+%
CAS: 162635-04-3 Formule moléculaire: C56H87NO16
Thermo Scientific Chemicals Colcemid, 98+%
CAS: 477-30-5 Formule moléculaire: C21H25NO5 Synonyme: Demecolcine; N-Methyl-N-desacetylcolchicine
Thermo Scientific Chemicals Adenylyl Cyclase Type V Inhibitor, NKY80
CAS: 299442-43-6 Formule moléculaire: C12H11N3O2 Poids moléculaire (g/mol): 229.24 Clé InChI: SOJUSNIBPPMLCC-UHFFFAOYNA-N Synonyme: NKY80; 2-Amino-7-(furan-2-yl)-7,8-dihydroquinazolin-5(6H)-one Nom IUPAC: 2-amino-7-(furan-2-yl)-5,6,7,8-tetrahydroquinazolin-5-one SMILES: NC1=NC=C2C(=O)CC(CC2=N1)C1=CC=CO1
Thermo Scientific Chemicals N-Acetyl-Asp-Glu-Val-Asp-7-amino-4-(trifluoromethyl)coumarin
CAS: 201608-14-2 Formule moléculaire: C30H34F3N5O13 Poids moléculaire (g/mol): 729.62 Clé InChI: GZDRODOYEFEHGG-NUDCOPPTSA-N Synonyme: Ac-DEVD-AFC Nom IUPAC: (4S)-4-{[(1S)-1-{[(1S)-2-carboxy-1-{[2-oxo-4-(trifluoromethyl)-2H-chromen-7-yl]carbamoyl}ethyl]carbamoyl}-2-methylpropyl]carbamoyl}-4-[(2S)-3-carboxy-2-acetamidopropanamido]butanoic acid SMILES: CC(C)[C@H](NC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](CC(O)=O)NC(C)=O)C(=O)N[C@@H](CC(O)=O)C(=O)NC1=CC=C2C(OC(=O)C=C2C(F)(F)F)=C1
Thermo Scientific Chemicals Salubrinal
CAS: 405060-95-9 Formule moléculaire: C21H17Cl3N4OS Synonyme: eIF-2alpha Inhibitor; SAL