Protease Inhibitors and Phosphatase Inhibitors
MilliporeSigma™ Calbiochem™ Hydroxychloroquine Sulfate
A cell-permeable compound that increases intralysosomal pH and impairs autophagic degradation process. Suppresses proliferation of human dermal fibroblasts (IC50 = 30 μM).
MilliporeSigma™ Calbiochem™ InSolution™Blebbistatin, Racemic
InSolution™Blebbistatin, Racemic, is a 50mm in 90% DMSO. A cell-permeable, selective, and reversible inhibitor of nonmuscle myosin II. Blocks cell blebbing and disrupts cell migration and cytoKinesis.
MilliporeSigma™ Calbiochem™ Cathepsin D/E Substrate, Fluorogenic
An internally quenched fluorogenic 11-mer peptide that acts as a sensitive and selective substrate for cathepsins D and E, but not cathepsins B, H, or L .
Thermo Scientific™ Pierce™ Protease Inhibitor Mini Tablets, EDTA-free
Thermo Scientific™ Pierce Protease Inhibitor Mini Tablets are broad-spectrum protease inhibitors that are highly effective at preventing proteolytic degradation for cell lysis and protein extraction experiments
Thermo Scientific™ PMSF Protease Inhibitor
Customize your protease inhibitor cocktail formulation with these small packages of individual protease inhibitor peptides and compounds.
Thermo Scientific™ AEBSF Protease Inhibitor
Customize your protease inhibitor cocktail formulation with these small packages of individual protease inhibitor peptides and compounds.
Thermo Scientific™ Aprotinin Protease Inhibitor
Customize your protease inhibitor cocktail formulation with these small packages of individual protease inhibitor peptides and compounds.
MilliporeSigma™ Calbiochem™ Protease Inhibitor Cocktail Set V, EDTA-Free
A cocktail of four protease inhibitors for the inhibition of serine, cysteine, but not metalloproteases.
MilliporeSigma™ Calbiochem™ InSolution™ Tamoxifen, 4-Hydroxy-, (Z)-
A 10 mM (2 mg/516 μL) sterile-filtered solution of (Z)-4-Hydroxytamoxifen in ethanol.
MilliporeSigma™ Calbiochem™ Cyclopamine, V. californicum
Cyclopamine, V. californicum, CAS 4449-51-8, is a cell-permeable steroidal alkaloid & cholesterol mimic that specifically antagonizes Sonic Hedgehog signaling through direct interaction with Smo.
MilliporeSigma™ Calbiochem™ InSolution™ PPACK, 2HCl
A 25 mM (5 mg/357 μl) sterile-filtered solution of PPACK, 2HCl in H2O.
MilliporeSigma™ Calbiochem™ SKP2 E3 Ligase Inhibitor I, C1
A cell-permeable rhodanine compound that upregulates cellular p21Cip1/Waf1 and p27Kip1 protein levels (10μM for 16 h in 501 Mel cultures) by preventing Skp2-Cks1-mediated substrate recruitment without affecting the F-box E3 ubiquitin ligase Skp2 interaction with Cks1 or the SCF (Skp1-cullin1-F-box) c
Thermo Scientific Chemicals Leupeptin, 90%, synthetic
CAS: 103476-89-7 Molecular Formula: 0·5 H2O4S
MilliporeSigma™ Calbiochem™ Metformin
An antihyperglycemic agent that lowers blood glucose levels without stimulating insulin secretion, promoting weight gain or causing hypoglycemia.