Protease Inhibitors and Phosphatase Inhibitors
MilliporeSigma™ Calbiochem™ Melatonin
A hormone that has been postulated as the mediator of photo-induced anti-gonadotropic activity in photoperiodic mammals.
MilliporeSigma™ Calbiochem™ Menin-MLL Interaction Inhibitor, MI-2-2
A cell-permeable thienopyrimidine compound
MilliporeSigma™ Calbiochem™ InSolution™ MEK1/2 Inhibitor III, PD0325901
The InSolution™ MEK1/2 Inhibitor III, PD0325901, also referenced under CAS 391210-10-9, controls the biological activity of MEK1/2. This small molecule/inhibitor is primarily used for Phosphorylation & Dephosphorylation applications.
MilliporeSigma™ Calbiochem™ 4-Hydroxynonenal
4-Hydroxynonenal, CAS 75899-68-2, is a major aldehyde product formed by peroxidation of ω-6-unsaturated fatty acids that is regarded as a specific marker of lipid peroxidation.
MilliporeSigma™ Calbiochem™ Glucose Transporter Inhibitor IV, WZB117
The Glucose Transporter Inhibitor IV, WZB117 controls the biological activity of Glucose Transporter.
MilliporeSigma™ Calbiochem™ Hydroxyurea
Anti-neoplastic agent that blocks DNA replication by inhibiting ribonucleotide reductase.
MilliporeSigma™ Calbiochem™ HIF-Hydroxylase Inhibitor, DMOG
The HIF-Hydroxylase Inhibitor, DMOG, also referenced under CAS 89464-63-1, controls the biological activity of HIF-Hydroxylase. This small molecule/inhibitor is primarily used for Cell Structure applications.
MilliporeSigma™ Calbiochem™ Methotrexate
Inhibits thymidylate synthetase, is a nonselective de novo purine synthesis inhibitor, and has a significant toxicity profile including hepatotoxicity, pneumonitis, and bone marrow suppress
MilliporeSigma™ Calbiochem™ InSolution™ MG-132
InSolution™ MG-132, CAS 133407-82-6, is provided as a 10 mM solution in DMSO. Acts as a potent, reversible proteasome inhibitor (Ki = 4 nM).
MilliporeSigma™ Calbiochem™ Mitochondrial Division Inhibitor, mdivi-1
The Mitochondrial Division Inhibitor, mdivi-1, also referenced under CAS 338967-87-6, controls the biological activity of yeast Dnm1 and mammalian Drp1.
MilliporeSigma™ Calbiochem™ Myeloperoxidase Inhibitor-I
The Myeloperoxidase Inhibitor-I, also referenced under CAS 5351-17-7, controls the biological activity of Myeloperoxidase. This small molecule/inhibitor is primarily used for Inflammation/Immunology applications.
MilliporeSigma™ Calbiochem™ c-Myc Inhibitor
The c-Myc Inhibitor, also referenced under CAS 403811-55-2, controls the biological activity of c-Myc.
MilliporeSigma™ Calbiochem™ PKA Inhibitor 14-22 Amide, Cell-Permeable, Myristoylated
PKA Inhibitor 14-22 Amide is myristoylated at the N-terminus that enhances its cell-permeability. The non-myristoylated version is shown to be a specific inhibitor of PKA (Ki = 36 nM).
MilliporeSigma™ Calbiochem™ Nocodazole
Inhibitor of mitosis.
MilliporeSigma™ Calbiochem™ Leupeptin, Hemisulfate, Microbial
Leupeptin hemisulfate, CAS 103476-89-7, is a reversible inhibitor of trypsin-like proteases and cysteine proteases.