Protease Inhibitors and Phosphatase Inhibitors
MilliporeSigma™ Calbiochem™ AEBSF, Hydrochloride
AEBSF, CAS 30827-99-7, is a specific irreversible inhibitor of chymotrypsin, kallikrein, plasmin, thrombin, trypsin, and related thrombolytic enzymes. A nontoxic alternative to PMSF and DFP.
MilliporeSigma™ Calbiochem™ Lactate Dehydrogenase A Inhibitor, FX11
Lactate Dehydrogenase A Inhibitor, FX11, CAS 213971-34-7, is a cell permeable, selective, reversible, NADH competitive inhibitor of lactate dehhydrogenase A (LDHA; Ki = 8μM for human liver LDHA).
MilliporeSigma™ Calbiochem™ Phosphatase Inhibitor Cocktail Set III
Phosphatase Inhibitor Cocktail Set III is a ready to use cocktail of four phosphatase inhibitors for broad-spectrum inhibition of both serine/threonine and protein tyrosine phosphatases.
MilliporeSigma™ Calbiochem™ InSolution™ Purmorphamine
Purmorphamine is a cell-permeable purine compound that induces osteoblast differentiation in C3H10T1/2 multipotent mesenchymal progenitor cells.
MilliporeSigma™ Calbiochem™ Rho Inhibitor, Rhosin
Rho Inhibitor, Rhosin, CAS 1173671-63-0, is a cell-permeable compound that directly targets Rho GEF binding domain (Kd = 354nM for RhoA), thereby prevents Rho from interacting with its GEFs.
MilliporeSigma™ Calbiochem™ InSolution™ γ-Secretase Inhibitor IX
InSolution™ g-Secretase Inhibitor IX, CAS 208255-80-5, is a 25 mM (5 mg/462 μl or 10 mg/924 μl) solution of g-secretase Inhibitor IX (DAPT; Cat. No. 565770) in DMSO.
MilliporeSigma™ Calbiochem™ SU5402
SU5402, CAS 215543-92-3, is a cell-permeable, reversible, and ATP-competitive inhibitor of the tyrosine kinase activity of FGFR1 (IC50 = 10 to 20 μM in the presence of 1 mM ATP).
MilliporeSigma™ Calbiochem™ Ru360
A cell-permeable oxygen-bridged dinuclear ruthenium amine complex that has been shown to bind to mitochondria with high affinity (Kd = 340 pM).
MilliporeSigma™ Calbiochem™ InSolution™ TGF-β RI Kinase Inhibitor VI, SB431542
The InSolution™ TGF-β RI Kinase Inhibitor VI, SB431542 controls the biological activity of TGF-β RI. Primarily used for Phosphorylation & Dephosphorylation applications.
MilliporeSigma™ Calbiochem™ Vacuolin-1
A cell-permeable triazine based compound that inhibits Ca
MilliporeSigma™ Calbiochem™ Valproic Acid, Sodium Salt
A cell-permeable, short-chained fatty acid that inhibits histone deacetylase (IC50 = 400 μM for HDAC1).
MilliporeSigma™ Calbiochem™ VEGFR3 Kinase Inhibitor, MAZ51
The VEGFR3 Kinase Inhibitor, MAZ51, also referenced under CAS 163655-37-6, controls the biological activity of VEGFR3 Kinase. This small molecule/inhibitor is primarily used for Phosphorylation & Dephosphorylation applications.
MilliporeSigma™ Calbiochem™ Wnt Agonist I in DMSO
The Wnt Agonist I in DMSO, also referenced under CAS 853220-52-7, controls the biological activity of Wnt. This small molecule/inhibitor is primarily used for Cancer applications.
MilliporeSigma™ Calbiochem™ Wnt Antagonist III, Box5
The Wnt Antagonist III, Box5 controls the biological activity of Wnt. This small molecule/inhibitor is primarily used for Cancer applications.
MilliporeSigma™ Calbiochem™ AMPK Inhibitor, Compound C
AMPK Inhibitor, Compound C, CAS 866405-64-3, is a cell-permeable compound that inhibits KDR/VEGFR2, ALK2/BMPR-I, and AMPK kinase activities (IC50 = 25.1, 148, and 234.6 nM, respectively).