Protease Inhibitors and Phosphatase Inhibitors
MilliporeSigma™ Calbiochem™ AMPK Inhibitor, Compound C
AMPK Inhibitor, Compound C, CAS 866405-64-3, is a cell-permeable compound that inhibits KDR/VEGFR2, ALK2/BMPR-I, and AMPK kinase activities (IC50 = 25.1, 148, and 234.6 nM, respectively).
MilliporeSigma™ Calbiochem™ InSolution™ AMPK Inhibitor, Compound C·2HCl
The InSolution™ AMPK Inhibitor, Compound C·2HCl, also referenced under CAS 866405-64-3, controls the biological activity of AMPK. This small molecule/inhibitor is primarily used for Phosphorylation & Dephosphorylation applications.
MilliporeSigma™ Calbiochem™ Aurora Kinase Inhibitor VI, ZM447439
The Aurora Kinase Inhibitor VI, ZM447439, also referenced under CAS 331771-20-1, controls the biological activity of Aurora Kinase. This small molecule/inhibitor is primarily used for Phosphorylation & Dephosphorylation applications.
MilliporeSigma™ Calbiochem™ Lactate Dehydrogenase A Inhibitor, FX11
Lactate Dehydrogenase A Inhibitor, FX11, CAS 213971-34-7, is a cell permeable, selective, reversible, NADH competitive inhibitor of lactate dehhydrogenase A (LDHA; Ki = 8μM for human liver LDHA).
MilliporeSigma™ Calbiochem™ Ro-20-1724
A cell-permeable, selective inhibitor of cAMP-specific phosphodiesterase (PDE IV; IC50 = 2 μM).
MilliporeSigma™ Calbiochem™ STAT3 Inhibitor XIII, C188-9
The Stat3 Inhibitor XIII, C188-9 controls the biological activity of Stat3. This small molecule/inhibitor is primarily used for Phosphorylation & Dephosphorylation applications.
MilliporeSigma™ Calbiochem™ Triptolide, Tripterygium wilfordii
A novel diterpene triepoxide isolated from the Chinese herb Tripterygium wilfordii that acts as a potent immunosuppressant and anti-inflammatory agent.
MilliporeSigma™ Calbiochem™ InSolution™ Tamoxifen, 4-Hydroxy-, (Z)-
A 10 mM (2 mg/516 μL) sterile-filtered solution of (Z)-4-Hydroxytamoxifen in ethanol.
MilliporeSigma™ Calbiochem™ InSolution™ Cyclopamine-KAAD
A cell-permeable potent analog of Cyclopamine that specifically inhibits Hedgehog (Hh) signaling with similar or lower toxicity.
MilliporeSigma™ Calbiochem™ Cyclopamine, V. californicum
Cyclopamine, V. californicum, CAS 4449-51-8, is a cell-permeable steroidal alkaloid & cholesterol mimic that specifically antagonizes Sonic Hedgehog signaling through direct interaction with Smo.
MilliporeSigma™ Calbiochem™ InSolution™ PPACK, 2HCl
A 25 mM (5 mg/357 μl) sterile-filtered solution of PPACK, 2HCl in H2O.
MilliporeSigma™ Calbiochem™ SKP2 E3 Ligase Inhibitor I, C1
A cell-permeable rhodanine compound that upregulates cellular p21Cip1/Waf1 and p27Kip1 protein levels (10μM for 16 h in 501 Mel cultures) by preventing Skp2-Cks1-mediated substrate recruitment without affecting the F-box E3 ubiquitin ligase Skp2 interaction with Cks1 or the SCF (Skp1-cullin1-F-box) c
MilliporeSigma™ Calbiochem™ Dicoumarol
A cell-permeable quinone reductase inhibitor with anticoagulant properties.
MilliporeSigma™ Calbiochem™ Adenosine 3',5'-cyclic Monophosphate, N6,O2'-Dibutyryl-, Sodium Salt
This Dibutyryl-cAMP, CAS 16980-89-5, is a cell-permeable cAMP analog that preferentially activates PKA.