Protein Purification
MilliporeSigma™ Calbiochem™ TRPV4 Agonist, GSK1016790A
A cell-permeable, potent, selective agonist of TRPV4 channel. Enhances Ca2+ flux in a variety of human and mouse cells (EC50 = 2.1 nM for human TRPV4).
MilliporeSigma™ Calbiochem™ LY 294002
LY294002, CAS 154447-36-6, is a cell-permeable, potent, reversible, and specific inhibitor of PI 3-kinase ((IC50 = 1.4 μM). Acts on the ATP-binding site.
Thermo Scientific™ Pierce™ Protease Inhibitor XL Capsules, EDTA-free
Pierce Protease Inhibitor XL Capsules protect proteins from proteolytic degradation through inhibition of the serine, cysteine, and aspartic acid proteases, and aminopeptidases that are typically present in cell lysate samples. Each tablet is sufficient for 500 mL of solution
MilliporeSigma™ Calbiochem™ Ribonuclease Inhibitor, Human, Recombinant, E. coli
The Ribonuclease Inhibitor, Human, Recombinant, E. coli controls the biological activity of Ribonuclease. This small molecule/inhibitor is primarily used for Protease Inhibitors applications.
MilliporeSigma™ Calbiochem™ Cathepsin B Substrate III, Fluorogenic
Sensitive fluorogenic substrate for the quantitative determination of cathepsin B activity.
Thermo Scientific™ Leupeptin Protease Inhibitor
Customize your protease inhibitor cocktail formulation with these small packages of individual protease inhibitor peptides and compounds.
MilliporeSigma™ Calbiochem™ ACE2 Inhibitor, MLN-4760
A cell-permeable, highly potent inhibitor of angiotensin converting enzyme 2 (ACE2; IC50 = 440 pM).
MilliporeSigma™ Calbiochem™ Smoothened Agonist, SAG
A cell-permeable Smoothened Agonist, SAG, CAS 364590-63-6, modulates the coupling of Smo with its downstream effector by interacting with the Smo heptahelical domain (KD = 59 nM).
MilliporeSigma™ Calbiochem™ mTOR Inhibitor XI, Torin1
mTOR Inhibitor XI, Torin1, CAS 1222998-36-8, is a cell-permeable, highly potent, ATP-competitive inhibitor of mTOR and DNA-PK (IC50 = 4.32 and 6.34 nM, respectively).
MilliporeSigma™ Calbiochem™ MEK1/2 Inhibitor III
The MEK1/2 Inhibitor III, also referenced under CAS 391210-10-9, controls the biological activity of MEK1/2. This small molecule/inhibitor is primarily used for Phosphorylation & Dephosphorylation applications.
MilliporeSigma™ Calbiochem™ NF-κB SN50, Cell-Permeable Inhibitor Peptide
NF-κB SN50, CAS 213546-43-3, is a cell-permeable peptide that contains the NLS sequence of NF-κB p50 linked to the hydrophobic region of K-FGF. Inhibits translocation of the NF-κB into the nucleus.
MilliporeSigma™ Calbiochem™ Menin-MLL Interaction Inhibitor, MI-2-2
A cell-permeable thienopyrimidine compound
MilliporeSigma™ Calbiochem™ JAK3 Inhibitor VI
The JAK3 Inhibitor VI, also referenced under CAS 856436-16-3, controls the biological activity of JAK3. This small molecule/inhibitor is primarily used for Phosphorylation & Dephosphorylation applications.
MilliporeSigma™ Calbiochem™ Ruthenium Red
A blocker of transmembrane Ca2+ fluxes (IC50 = 7 μM) that attenuates capsaicin-induced cation channel opening.
MilliporeSigma™ Calbiochem™ Val-boroPro
An orally available amino boronic acid dipeptide with antihyperglycemic and anticancer properties