Protein Analysis Reagents

Guanidine Hydrochloride (Colorless-to-White Crystals), Fisher BioReagents™

For isolation of RNA from cell extracts | CAS: 50-01-1 | CH6ClN3

MilliporeSigma™ Calbiochem™ Rho Kinase Inhibitor

The Rho kinase inhibitor, CAS 872543-07-6, is a cell-permeable, highly specific, reversible, potent, and ATP-competitive inhibitor of Rho-associated kinase (ROCK; Ki = 1.6 nM).

MilliporeSigma™ Calbiochem™ InSolution™ γ-Secretase Inhibitor IX

InSolution™ g-Secretase Inhibitor IX, CAS 208255-80-5, is a 25 mM (5 mg/462 μl or 10 mg/924 μl) solution of g-secretase Inhibitor IX (DAPT; Cat. No. 565770) in DMSO.

MilliporeSigma™ Calbiochem™ Cathepsin D/E Substrate, Fluorogenic

An internally quenched fluorogenic 11-mer peptide that acts as a sensitive and selective substrate for cathepsins D and E, but not cathepsins B, H, or L .

MilliporeSigma™ Calbiochem™ Forskolin, 7-Deacetyl-7-[O-(N-methylpiperazino)-γ-butyryl]-, Dihydrochloride

Chemically-modified forskolin with greater stability and water solubility than the parent compound.

Thermo Scientific Chemicals Protease Inhibitor Cocktail, for general use

MilliporeSigma™ Calbiochem™ (±)-Blebbistatin

(±)-Blebbistatin, CAS 674289-55-5, is a cell-permeable, selective, and reversible inhibitor of nonmuscle myosin II. Blocks cell blebbing and disrupts cell migration & cytoKinesis in vertebrate cells.

MilliporeSigma™ Calbiochem™ CA-074 Me

CA-074 Me, CAS 147859-80-1, is a cell-permeable analog of CA-074 that acts as an irreversible inhibitor of intracellular cathepsin B.

MilliporeSigma™ Calbiochem™ CaCC Blocker IV, Benzbromarone

A cell-permeable uricosuric agent that, in addition to its known efficacy in gout treatment, acts as a reversible CaCC blocker and is reported to be more potent than NFA (Cat

MilliporeSigma™ Calbiochem™ RIP1 Inhibitor II, 7-Cl-O-Nec-1

RIP1 Inhibitor II, 7-Cl-O-Nec-1, CAS 852391-15-2, is a cell-permeable, highly selective RIP1 inhibitor. Blocks RIP1-dependent necroptosis (EC50 = 206nM in Jurkat cells).

MilliporeSigma™ Calbiochem™ Bortezomib

Bortezomib, CAS 179324-69-7, is a cell-permeable, selective, slowly reversible inhibitor of 20S proteasome β5 ChTL/chymotrypsin- over β1 CL/caspase- and β2 TL/trypsin-like activity.

MilliporeSigma™ Calbiochem™ InSolution™ Smoothened Agonist, SAG

InSolution™ Smoothened Agonist, SAG, is a 10 mM (500 μg/86 μl) solution of Smoothened Agonist, SAG (Cat. No. 566660) in H₂O.

MilliporeSigma™ Calbiochem™ STAT3 Inhibitor III, WP1066

STAT3 Inhibitor III, WP1066, CAS 857064-38-1, is a cell-permeable AG490 tyrphostin analog that acts as a STAT3 pathway inhibitor. A potent anti-tumor agent.

MilliporeSigma™ Calbiochem™ STAT5 Inhibitor III, Pimozide

The STAT5 Inhibitor III, Pimozide, also referenced under CAS 2062-78-4, controls the biological activity of STAT5.

Thermo Scientific Chemicals Phosphatase Inhibitor Cocktail I