Protease Inhibitors and Phosphatase Inhibitors
MilliporeSigma™ Calbiochem™ Rac Inhibitor III, EHop-016
The Rac Inhibitor III, EHop-016 controls the biological activity of Rac. This small molecule/inhibitor is primarily used for Membrane applications.
MilliporeSigma™ Calbiochem™ InSolution™ Y-27632
Y-27632A, CAS 146986-50-7, is a cell-permeable, reversible, inhibitor of Rho kinases (Ki = 140 nM for p160ROCK). Enhances survival & cloning efficiency of ESC without affecting their pluripotency.
MilliporeSigma™ Calbiochem™ Aurora Kinase Inhibitor VI, ZM447439
The Aurora Kinase Inhibitor VI, ZM447439, also referenced under CAS 331771-20-1, controls the biological activity of Aurora Kinase. This small molecule/inhibitor is primarily used for Phosphorylation & Dephosphorylation applications.
MilliporeSigma™ Calbiochem™ Temozolomide
A cell-permeable, orally bioavailable, blood-brain barrier-permeant MTIC [5-(3-methyltriazen-1-yl-)-imidazole-4-carboxamide] prodrug whose in vivo DNA alkylating activity is employed in anticancer ther
MilliporeSigma™ Calbiochem™ Gemcitabine, HCl
A bioavailable, moderately toxic, deoxyctytidine analog with anti-metabolite and anti-tumor properties
MilliporeSigma™ Calbiochem™ Epoxomicin, Synthetic
Epoxomicin, Synthetic, CAS 134381-21-8, is a potent, specific, and irreversible inhibitor of chymotrypsin-like, trypsin-like, and peptidyl-glutamyl peptide hydrolyzing activities of the proteasome.
MilliporeSigma™ Calbiochem™ InSolution™ AMPK Inhibitor, Compound C·2HCl
The InSolution™ AMPK Inhibitor, Compound C·2HCl, also referenced under CAS 866405-64-3, controls the biological activity of AMPK. This small molecule/inhibitor is primarily used for Phosphorylation & Dephosphorylation applications.
MilliporeSigma™ Calbiochem™ SU5402
SU5402, CAS 215543-92-3, is a cell-permeable, reversible, and ATP-competitive inhibitor of the tyrosine kinase activity of FGFR1 (IC50 = 10 to 20 μM in the presence of 1 mM ATP).
MilliporeSigma™ Calbiochem™ AMPK Inhibitor, Compound C
AMPK Inhibitor, Compound C, CAS 866405-64-3, is a cell-permeable compound that inhibits KDR/VEGFR2, ALK2/BMPR-I, and AMPK kinase activities (IC50 = 25.1, 148, and 234.6 nM, respectively).
MilliporeSigma™ Calbiochem™ Oxidized ATP (oATP)
A 2',3'-dialdehyde derivative of ATP that is commonly used to affinity label nucleotide sites in enzymes
MilliporeSigma™ Calbiochem™ InSolution™ Purmorphamine
Purmorphamine is a cell-permeable purine compound that induces osteoblast differentiation in C3H10T1/2 multipotent mesenchymal progenitor cells.
Thermo Scientific™ Leupeptin Protease Inhibitor
Customize your protease inhibitor cocktail formulation with these small packages of individual protease inhibitor peptides and compounds.
MilliporeSigma™ Calbiochem™ Hydroxychloroquine Sulfate
A cell-permeable compound that increases intralysosomal pH and impairs autophagic degradation process. Suppresses proliferation of human dermal fibroblasts (IC50 = 30 μM).
MilliporeSigma™ Calbiochem™ HSP70 Inhibitor, PES-Cl
Directly binds to HSP70 and disrupts its interaction with client proteins..
MilliporeSigma™ Calbiochem™ Roscovitine
A potent, reversible, and selective inhibitor of Cdks that exhibits about 10-fold greater efficacy towards p34-cdk1 and p33-cdk2 and 20-fold greater efficacy towards p33-cdk5 relative to Olomoucine.