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Protein Modification Reagents

Chemical agents used to modify the amino acid side chains of proteins in order to alter their native charges, block or expose reactive binding sites, inactivate functional groups, and change functional groups to create targets for crosslinking and labeling.
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1 – 15 of 121 results
1

Thermo Scientific™ TMS(PEG)12 Branched Methyl-PEG-NHS-Ester Reagent

A three-branched, polyethylene glycol compound (3 times 12 PEG units) activated as an NHS ester for covalent PEGylation of primary amines on proteins or assay surfaces.

2

MilliporeSigma™ Calbiochem™ 5'-Deoxy-5'-methylthioadenosine

Inhibits protein carboxymethyltransferase, induces apoptosis in leukemia U937 cells.

5

Thermo Scientific™ Pierce™ Sodium meta-Periodate

Gently oxidize glycoprotein carbohydrate sugars to create reactive aldehydes (carbonyls) for crosslinking and immobilization using NaIO4 (CAS 7790-28-5).

6

Thermo Scientific™ Immobilized Ficin (Agarose Resin)

Enable controlled antibody fragmentation, especially of mouse IgG1, with this sulfhydryl-specific ficin protease immobilized onto beaded agarose resin.

8

MilliporeSigma™ Novagen™ Overnight Express™ Autoinduction System 1

Induces protein expression without monitoring cell density.

Content And Storage 15°C to 30°C
9

Thermo Scientific™ Pierce™ Hydroxylamine-HCl

NH2OH (CAS 7803-49-8) to cleave Asn-Gly peptide bonds or deprotect sulfhydryls following S-acetylthioacetate modification with SATA reagent.

10

Thermo Scientific™ MA(PEG)12 Methyl-PEG-Amine Compound

MA(PEG)n: methyl- and amine-capped polyethylene glycol compounds containing 4 to 24 PEG units; use for surface-modification and molecule-pegylation applications.

Content And Storage Upon receipt store product at -20°C protected from moisture. Product is shipped at ambient temperature.
Product Type Amine Compound
Form Solid
Spacer 12 ethylene glycol units
Solubility Water
Reactive Moiety Amine, Primary Amine
Label Type Polyethylene Glycol (PEG), Blocking Groups
Chemical Reactivity Aldehyde
11

Thermo Scientific™ Pierce™ Premium Grade TCEP-HCl

Optimize applications where product integrity and risk minimization are paramount with our highest quality formulation of this disulfide reducing agent.

Content And Storage Upon receipt store product at room temperature in sealed container to prevent oxidation. Product is shipped at ambient temperature.
Product Type Disulfide Reducing Reagent
Product Line Pierce
12

Thermo Scientific™ WELQut Protease (5 U/μL)

Thermo Scientific™ WELQut Protease is a highly specific serine protease cleaving outside the WELQX recognition motif to remove N-terminal protein fusion tags.

13

Invitrogen™ Thiol and Sulfide Quantitation Kit  DFS Item

Ultrasensitive colorimetric assay for quantifying both protein and nonprotein thiols

14

Thermo Scientific™ CA(PEG)8 Carboxy-PEG-Amine Compound

CA(PEG)n: pegylated amino acids of the form carboxy-PEG-amine; with 4 to 24 polyethylene glycol units; for surface- and molecule-pegylation applications.

Content And Storage Store desiccated at 4°C. Shipped at ambient temperature.
Product Type Amine Compound
Spacer 8 ethylene glycol units
Solubility Water
Reactive Moiety Amine, Carboxylic Acid, Primary Amine
Label Type Conjugating Groups, Polyethylene Glycol (PEG)
15

Thermo Scientific™ Pierce™ Traut's Reagent (2-iminothiolane)

2-Iminothiolane-HCl (CAS 4781-83-3); an amine-reactive thiolation reagent to cap protein primary amines with sulfhydryl groups for immediate crosslinking.