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MilliporeSigma™ Angiotensin Converting Enzyme, His·Tag™, Human, Recombinant, NSO Cells

Catalog No. 17687110UG
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10 μg
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Catalog No. Quantity
17687110UG 10 μg
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Catalog No. 17687110UG Supplier MilliporeSigma™ Supplier No. 17687110UG

Description

Type I membrane protein that exists in two isoforms, somatic and germinal

  • Recombinant, human ACE ectodomain (amino acids 30-1261) fused at the C-terminus to a His•Tag™ sequence and expressed in NSO cells
  • ACE is a zinc metallopeptidase that cleaves the C-terminal dipeptide from angiotensin I to produce the potent vasopressor octapeptide angiotensin II
  • Inactivates bradykinin by the sequential removal of two C-terminal dipeptides
  • ACE is a type I membrane protein that exists in two isoforms, somatic and germinal
  • By SDS-PAGE, the apparent molecular mass of the glycosylated protein appears larger than 120 kDa under either reducing or non-reducing condition

Specifications

Concentration Concentration Label: Please refer to vial label for lot-specific concentration
Formulation In 75mM NaCl, 12.5mM Tris, 500nM ZnCl₂, 40% glycerol, pH 7.5
Purity ≥95% by SDS-PAGE
Content And Storage ≤-70°C
Form Liquid
Quantity 10 μg
Synonym Peptidyl-Dipetidase A, ACE
Product Type Angiotensin Converting Enzyme (ACE)