missing translation for 'onlineSavingsMsg'
Learn More
Please login to your online account to display your discounted pricing

Thermo Scientific™ Pierce™ CHAPS

Non-denaturing Zwitterionic detergents that disrupt nonspecific protein interactions with less protein aggregation than nonionic detergents.

$227.16 - $1,852.31


Description CHAPS
Formulation 3-[(3-Cholamidopropyl)dimethylammonio]-1-propanesulfonate
Properties Zwitterionic, Dialyzable
View More Specs

Products ${productFamilyLength}
Catalog Number Mfr. No. Description Quantity Price Quantity  
Catalog Number Mfr. No. Description Quantity Price Quantity  
PI28299 Thermo Scientific™
CHAPS 100g Pack for $1,852.31
PI28300 Thermo Scientific™
CHAPS 5g Pack for $227.16


Thermo Scientific™ CHAPS is a zwitterionic detergent that is especially well suited for protecting the native state of proteins.

CHAPS is a sulfobetaine derivatives of cholic acid. This zwitterionic detergent is useful for membrane protein solubilization when it is important to maintain protein activity. CHAPS detergent is soluble over a wide range of pH (2 to 12) and are easily removed from solution by dialysis because of their high critical micelle concentration (CMC).


  • Versatile zwitterionic detergents
  • Provide mild but effective lysis of cultured mammalian cells
  • Nondenaturing and generally do not inactivate protein functions
  • Can be removed from solution by dialysis
  • Commonly used for isoelectric focusing (IEF) and 2D electrophoresis

Properties of CHAPS detergent:

  • Chemical Name: 3-[(3-Cholamidopropyl)dimethylammonio]-1-propanesulfonate
  • Molecular Weight: 614.88
  • Detergent Class: Zwitterionic
  • Aggregation Number: 10
  • Micelle Molecular Weight: 6149
  • Critical Micelle Concentration (CMC): 8 to 10mM (0.4920 to 0.6150%, w/v)
  • Cloud Point: ≥ 100°C
  • Dialyzable: Yes

Description & Specifications


Zwitterionic, Dialyzable