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  6. Thermo Scientific™ CHAPS Detergent (3-((3-cholamidopropyl) dimethylammonio)-1-propanesulfonate)

Thermo Scientific™ CHAPS Detergent (3-((3-cholamidopropyl) dimethylammonio)-1-propanesulfonate)

Catalog No. p-4530894
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100 g
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PI28299 100 g
PI28300 5 g
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Catalog No. PI28299 Supplier Thermo Scientific™ Supplier No. 28299
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Description

Non-denaturing Zwitterionic detergents that disrupt nonspecific protein interactions with less protein aggregation than nonionic detergents.

Thermo Scientific™ CHAPS is a zwitterionic detergent that is especially well suited for protecting the native state of proteins.

CHAPS is a sulfobetaine derivatives of cholic acid. This zwitterionic detergent is useful for membrane protein solubilization when it is important to maintain protein activity. CHAPS detergent is soluble over a wide range of pH (2 to 12) and are easily removed from solution by dialysis because of their high critical micelle concentration (CMC).

Highlights:

  • Versatile zwitterionic detergents
  • Provide mild but effective lysis of cultured mammalian cells
  • Nondenaturing and generally do not inactivate protein functions
  • Can be removed from solution by dialysis
  • Commonly used for isoelectric focusing (IEF) and 2D electrophoresis

Properties of CHAPS detergent:

  • Chemical Name: 3-[(3-Cholamidopropyl)dimethylammonio]-1-propanesulfonate
  • Molecular Weight: 614.88
  • Detergent Class: Zwitterionic
  • Aggregation Number: 10
  • Micelle Molecular Weight: 6149
  • Critical Micelle Concentration (CMC): 8 to 10mM (0.4920 to 0.6150%, w/v)
  • Cloud Point: ≥ 100°C
  • Dialyzable: Yes

 

Specifications

Product Type Detergent
Content And Storage Store at Room Temperature
Form Powder
Reagent Type Detergent (Pure)
Quantity 100 g

For Research Use Only. Not for use in diagnostic procedures.