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Hamilton™ PRP-1 Reversed Phase HPLC Columns, 5um Particle Size

Stable alternative to C8 or C18 Columns

$713.19 - $975.13


Column Format Analytical
Column Type PS-DVB
Particle Size 5μm
Technique HPLC
Film Thickness 5μm
View More Specs
Catalog Number Mfr. No. Diameter (Metric) Inner Material Length (Metric) Price Quantity    


4.1mm Stainless Steel 150mm Each for $887.17


4.1mm Stainless Steel 50mm Each for $713.19


4.6mm PEEK 150mm Each for $975.13
Description & Specifications


Column Format Analytical
Column Type PS-DVB
Particle Size 5μm
Technique HPLC
Film Thickness 5μm
For Use With Organic compounds, pharmaceuticals, Steroids, Nucleic Acids, Vitamins, herbicides
Max. Pressure 5000psi
Mobile Phase Compatibility pH 1 to 13, 0 to 100% aqueous, organic modifier
Packing Material PS-DVB
pH 1 to 13
Phase Polymeric reverse phase
Pore Size 100Å
Stationary Phase PS-DVB
Temperature (Metric) Range 5 to 85°C
Type HPLC Column
USP Type L21

Wide pH Stability

  • Stability from pH 1 to 13 allows for the analysis of samples at high pH (8-13) without the possibility of column degradation or loss of efficiency. An expanded pH range also allows samples to be chromatographed while ionized.
  • Good Sample Recovery
    • Since PRP-1 is made entirely of poly(styrene-divinylbenzene), there are no silanol groups to cause sample loss, thus the recovery and quantitation of labile and reactive samples is enhanced.
  • Consistent Reproducibility
    • PRP-1 reversed phase columns are ideal for applications that require a high degree of column-to-column and batch to batch consistency (i.e., quality assurance, clinical trials). Unlike C8 or C18 columns, PRP-1 has no stationary phase coating.
  • Easy Sample Scale-up
    • Columns are available prepacked and tested in a variety of sizes, varying from analytical to semi-prep and preparative scale. Consistent packing material allows linear method scale-up.
  • Long Life (Excellent Durability)
    • PRP-1 columns are packed with a poly(styrene-divinylbenzene) material. This support is pressure stable up to 5,000psi, and cross-linked to prevent shrinkage or swelling (common in other polymeric columns). Since the support is entirely polymeric with no silica to deteriorate, column lifetime is longer for PRP-1 than silica C4, C8 or C18 columns.

    • Column internal diameters: 4.1 and 4.6mm
    • Two column materials: 316 stainless steel and PEEK
    • Analytical guard columns