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Invitrogen™ Alexa Fluor™ 647-Poly-GT Peptide Substrate 
A general AlexaFluor647-labeled peptide substrate consisting of a polymer of glutamate, and tyrosine that is used to monitor tyrosine kinase acitivty.
Supplier: Invitrogen™ PV5693
Description
A general AlexaFluor647-labeled peptide substrate consisting of a polymer of glutamate, and tyrosine that is used to monitor tyrosine kinase acitivty.
For use in combination with the LanthaScreen™ Eu-PY20 Antibody (Cat. No. PV5696) to evaluate inhibitors in medium to high throughput screening applications.
Greener Choice Claims
- Environmental benefits include:
- Renewable Energy
Specifications
| Biochemical europium phospho-specific activity | |
| 30 μM AlexaFluor 647 Poly-GT peptide substrate in 10 mM HEPES, 137 mM NaCl, 2.7 mM KCl, pH 7.5 (HEPES buffered saline). Store at -20°C and protect from light. |
|
| Liquid | |
| 1 nmol | |
| Peptide-Based Substrate | |
| Tyrosine Kinases | |
| Alexa Fluor™ 647 | |
| ABL1 G250E, CSF1R, CSK, EPHA5, KIT, PDGFRA V561D, SYK, TYRO3, ZAP70, FGFR1, FGFR2, EGFR, EPHB2, FGFR4, IGF1R, LYNA, MATK, MERTK, NTRK3, RET V804L, TEK, FLT1, MUSK, SRCN1, ABL1 E255K, EPHA4, FYN, PTK2, PTK2B, RET, ABL1 T315I, EPHA3, EPHB4, FLT3, FLT4, INSR, LCK, YES1, EGFR L858R, ERBB4, KDR, MET, TNK2, ABL1, ABL2, AXL, FGFR3, FGR, HCK, KIT V654A, EPHA1, EPHA8, EPHB3, INSRR, LYNB, NTRK1, PDGFRA D842V, SRMS, EGFR L861Q, EPHA2, FER, LTK, PDGFRA, EPHA7, EPHB1, FRK, ITK, FLT3 D835Y, SRC, BTK, FES, ERBB2, NTRK2 | |
| EGFR |
| Far-Red | |
| Fluorescence | |
| LanthaScreen™ | |
| Random (Glu:Tyr) polymer in a ratio of 4:1 | |
| Kinase Substrate | |
| 340/665 nm | |
| Dry Ice | |
| TR-FRET |
For Research Use Only. Not for use in diagnostic procedures.