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Invitrogen™ Human PIK3C3 (hVPS34), GST Tag Recombinant Protein 
Recombinant Protein
Supplier: Invitrogen™ PV5127
Description
For maximum recovery please spin prior to use. Unless noted below, aliquots of the 5 ÎĽg, 10 ÎĽg and 20 ÎĽg sizes of kinase are not recommended as materials can be used in original packaging until exhausted. For larger sizes, the number of freeze/thaws may be reduced by preparing aliquots, aliquots below 20 ÎĽL are not recommended. Please never store a kinase diluted. If properly stored at -80C, this product is guaranteed for 6 months from date of purchase. Protein Form: Full Length
PIK3C3 (hVPS34) is the sole class III member of the PI3 Kinase family. PIK3C3 phosphorylates phosphatidylinositol (PI) to produce phosphatidylinositol 3-phosphate [PI(3)P], which recruits downstream effectors containing FYVE and Phox domains to membranes. PIK3C3 is involved in coupling nutrient signaling to mTOR and also plays a role in autophagy and intracellular trafficking. Involved in regulation of degradative endocytic trafficking and required for the abcission step in cytokinesis, probably in the context of PI3KC3-C2. Involved in the transport of lysosomal enzyme precursors to lysosomes. Required for transport from early to late endosomes.Specifications
| Q8NEB9 | |
| Kinase Assay | |
| 5289 | |
| Human PIK3C3 (hVPS34), GST Tag | |
| RUO - research use only | |
| VPS34 | |
| Unconjugated | |
| Recombinant | |
| Full length | |
| Baculovirus |
| See Label | |
| 50 mM tris with 0.02% CHAPS, 0.5 mM EDTA, 150 mM NaCl, 2 mM DTT, 50% glycerol and no preservative; pH 7.5 | |
| 129 kDa | |
| 1 mg | |
| 5330434F23Rik; catalytic phosphatidylinositol 3-kinase 3; catalytic subunit type 3 Antibody; class 3 phosphoinositide-3-kinase; Class III PI 3-kinase; hVps34; hVps34 Antibody; OTTMUSP00000023341; OTTMUSP00000023350; phosphatidylinositol 3-kinase; Phosphatidylinositol 3-kinase catalytic subunit type 3; phosphatidylinositol 3-kinase p100 subunit; phosphatidylinositol 3-kinase, catalytic subunit type 3; Phosphoinositide-3-kinase class 3; phosphoinositide-3-kinase, class 3; PI3K type 3; PI-3 K Vps34p; pi3kc3; PI3-kinase type 3; Pik3c3; PIK3C3 Antibody; PtdIns-3-kinase type 3; VPS34 | |
| PI3 Kinase Family | |
| Human | |
| GST-tag | |
| -80°C, Avoid Freeze/Thaw Cycles | |
| Liquid |