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MP Biomedicals Collagenase from Clostridium histolyticum


Enzyme responsible for break down of peptide bonds in collagen

Manufacturer: mp biomedicals  02195109.1

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Catalog No. ICN1951091

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Description & Specifications

Specifications

Product Name Collagenase
Format Lyophilized Powder
Concentration >125U/mg
Color Brown
Inhibitors Metal chelating agents such as Cysteine, EDTA or o-Phenanthroline
Source Clostridium histolyticum
pH 7 to 9
Molecular Weight 105000 and 57400
Quantity 100mg
For Use With (Application) Approved for medical uses for treatment of Dupuytren's contracture (Xiaflex) and wound healing
Storage Requirements 4°C

Assist in destroying extracellular structures in pathogenesis of bacteria such as Clostridium. These enzymes are exotoxins (a virulence factor) and help to facilitate the spread of gas gangrene. They normally target the connective tissue in muscle cells and other body organs.

  • Synonyms: Clostridiopeptidase A
  • CAS Number: 9001-12-1
  • EC Number: 232-582-9
  • MDL Number: MFCD00130830
  • Format: Dialyzed, lyophilized brown lumpy powder
  • Specific Activity: >125U/mg
  • Solubility: Dissolve enzyme at concentration of 1mg/mL in 0.05M TES with 0.36mM calcium chloride, pH 7.5

Approved for medical uses for treatment of Dupuytren's contracture (Xiaflex) and wound healing.