Protein Modification Reagents
Thermo Scientific™ Proteinase K Powder (≥30 U/mg)
Cleave at the carboxyl-side of aliphatic, aromatic or hydrophobic residues and digest-inactivate DNase and RNase in nucleic acid purification using this protease.
Thermo Scientific™ Pierce™ Alkylating Reagents
Alkylating reagents provided in single-use, pre-weighed formats to streamline protein preparation workflows.
Thermo Scientific™ Pierce™ Mercaptoethylamine-HCl
Pure, crystalline 2-aminoethanethiol (2-MEA-HCl, also called cysteamine-HCl), CAS 156-57-0; selectively reduces antibody hinge-region disulfide bonds.
MilliporeSigma™ Calbiochem™ BAPTA/AM
Can be loaded into wide variety of cells, where it is hydrolyzed by cytosolic esterases and is trapped intracellularly as the active chelator BAPTA
MilliporeSigma™ Calbiochem TCEP, Neutral
Ready-to-use stable, neutral form of popular disulfide-reducing agent TCEP, Hydrochloride
MilliporeSigma™ THP, Calbiochem™,
Molecular Formula: C9H21O3P Molecular Weight (g/mol): 208.238 InChI Key: YICAEXQYKBMDNH-UHFFFAOYSA-N Synonym: tris hydroxypropyl phosphine,3,3',3-phosphinetriyltris propan-1-ol,3-bis 3-hydroxypropyl phosphanyl propan-1-ol,pirugon pp 40,tris-3-hydroxypropyl phosphine PubChem CID: 11006655 IUPAC Name: 3-[bis(3-hydroxypropyl)phosphanyl]propan-1-ol SMILES: C(CO)CP(CCCO)CCCO
MilliporeSigma™ Calbiochem™ Thrombospondin, Human Platelets
Blocks FGF-induced neovascularization of rat cornea.
Thermo Scientific™ WELQut Protease (5 U/μL)
Thermo Scientific™ WELQut Protease is a highly specific serine protease cleaving outside the WELQX recognition motif to remove N-terminal protein fusion tags.
Thermo Scientific™ Immobilized Trypsin, TPCK Treated (Agarose Resin)
Cleave the carboxyl-side of Arg and Lys residues with trypsin that isTPCK-treated to block chymotrypsin activity; its immobilized form allows enzyme removal after digestion.
MilliporeSigma™ Angiotensin Converting Enzyme, His·Tag™, Human, Recombinant, NSO Cells
Type I membrane protein that exists in two isoforms, somatic and germinal
MilliporeSigma™ Angiotensin Converting Enzyme-2, His·Tag™, Human, Recombinant, NSO Cells
Plays important role in regulating cardiovascular and renal functions
Thermo Scientific™ Pierce™ DTT (Dithiothreitol)
Reduce disulfides in biological buffers and sample loading buffers with pure, crystalline dithiothreitol (DTT), the most popular protein disulfide reducing agent.
Thermo Scientific™ Immobilized Pepsin (Agarose Resin)
Generate and purify Fab and F(ab')2 fragments from antibodies with acidic endopeptidase (pepsin) immobilized onto beaded agarose resin.
Thermo Scientific™ Pierce™ Sodium meta-Periodate
Gently oxidize glycoprotein carbohydrate sugars to create reactive aldehydes (carbonyls) for crosslinking and immobilization using NaIO4 (CAS 7790-28-5).
Thermo Scientific™ Pierce™ MMTS (methyl methanethiosulfonate)
Methyl methanethiosulfonate (CAS 2949-92-0); reversibly blocks cysteines (sulfhydryl groups) to facilitate study of enzyme activation and protein functions.