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Invitrogen™ TSSC1 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA556683

Catalog No. PIPA556683


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This chemical may require us to obtain additional information for our regulatory and chemical compliance records. If required, we will contact you for this information once your order is placed.


Description

Description

Immunogen sequence: VILSNMVSIS SEPFGHLVDD DDISDQEDHR SEEKSKEPLQ DNVIATYEEH EDSVYAVDWS SADPWLFASL SYDGRLVINR VPRALKYH Highest antigen sequence identity to the following orthologs: Mouse - 92%, Rat - 92%.

TSSC1 has been reported in PMID 9403053 as one of several tumor-suppressing sub transferable fragments located in the imprinted gene domain of 11p15.5, an important tumor-suppressor gene region. Alterations in this region have been associated with the Beckwith-Wiedemann syndrome, Wilms tumor, rhabdomyosarcoma, adrenocortical carcinoma, and lung, ovarian, and breast cancer. Alignment of this gene to genomic sequence data suggests that this gene resides on chromosome 2 rather than chromosome 11.
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