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Invitrogen™ Human NTRK3 (TRKC), His Tag Recombinant Protein
Recombinant Protein
Supplier: Invitrogen™ PV3617
Description
For maximum recovery please spin prior to use. Unless noted below, aliquots of the 5 ÎĽg, 10 ÎĽg and 20 ÎĽg sizes of kinase are not recommended as materials can be used in original packaging until exhausted. For larger sizes, the number of freeze/thaws may be reduced by preparing aliquots, aliquots below 20 ÎĽL are not recommended. Please never store a kinase diluted. If properly stored at -80C, this product is guaranteed for 6 months from date of purchase. Protein Form: Recombinant, Catalytic Domain, Cytoplasmic
NTRK3 (TRKC) belongs to the neurotrophic factor family of related polypeptides central to the development and maintenance of the mammalian nervous system. Known substrates for the TRK receptors are SHC, PI-3 kinase, and PLCG1. The different isoforms do not have identical signaling properties. The protein is widely expressed, mainly in the nervous tissue. The isoform B is expressed in a relatively large amount in the adult brain comparatively to fetal brain. TRKC is subject to ligand-mediated auto-phosphorylation. The protein structure contains 2 immunoglobulin-like C2-type domains and 2 leucine-rich (LRR) repeats.Specifications
Q16288 | |
Kinase Assay | |
4916 | |
Human NTRK3 (TRKC), His Tag | |
AW125844; ETS related protein-neurotrophic receptor tyrosine kinase fusion protein; ETV6-NTRK3 fusion; gp145(trkC); GP145-TrkC; neural receptor protein-tyrosine kinase (trkC); neurotrophic receptor tyrosine kinase 3; Neurotrophic tyrosine kinase receptor type 3; neurotrophic tyrosine kinase, receptor, type 3; neurotrophin-3; NT-3 growth factor receptor; NTRK3; Ntrk3_tv3; TrkC; trk-C; trkC tyrosine kinase; tyrosine kinase receptor; tyrosine kinase receptor C | |
Neurotrophic Receptor (NTRK) Kinase Family | |
Unconjugated | |
Recombinant | |
-80°C, Avoid Freeze/Thaw Cycles | |
Tyrosine Kinases | |
LanthaScreen™ Antibody, LanthaScreen™ Substrate, Z'-LYTE™ | |
neurotrophic tyrosine kinase, receptor, type 3 | |
Kinases & Inhibitors | |
Liquid | |
Signal Transduction |
See Label | |
50 mM tris HCl with 0.05% Triton X-100, 0.5 mM EDTA, 150 mM NaCl, 4 mM DTT, 50% glycerol and no preservative; pH 7.5 | |
41.2 kDa | |
10 ÎĽg | |
TrkC | |
510-825 | |
Human | |
His-tag | |
Biochemical phospho-specific activity (no antibody), Biochemical terbium phospho-specific activity, Biochemical europium phospho-specific activity | |
Dry Ice | |
NTRK3 | |
Baculovirus | |
Recombinant, Catalytic Domain, Cytoplasmic | |
Receptor Tyrosine Kinases |