Invitrogen™ Myosin heavy chain 1 Recombinant Rabbit Monoclonal Antibody (PSH05-12)

Description

Positive Control: Human skeletal muscle tissue, mouse skeletal muscle tissue, rat skeletal muscle tissue. Tissue Specificity: Tissue enriched (skeletal). Subcellular Location: Cytoplasm, myofibril. Sequence Similarities: 100% Mouse/Rat. Predicted band size: 223 kDa.

Myosin is a protein which is known to interact with actin in muscle and non-muscle cells. It contains two identical heavy chains and four light chains. Myosin molecules consist of two major regions: tails (rods) and heads. They aggregate into filaments through the tail region and interact with actin and with ATP through the head region. Multiple forms of myosin heavy chains exist for each muscle type-skeletal, cardiac, smooth and non-muscle isomyosin forms exist in different types of skeletal muscle, depending on the physiological function of the muscle. They are designated at type I (slow twitch) and type II (fast twitch).