Learn More
Invitrogen™ Human IKBIP (aa 100-189) Control Fragment Recombinant Protein
Recombinant Protein
Supplier: Invitrogen™ RP97813
Description
Highest antigen sequence indentity to the following orthologs: Mouse (70%), Rat (70%). This recombinant protein control fragment may be used for blocking experiments with the corresponding antibody, PA5-58491 (PA5-58491. In IHC/ICC and WB experiments, we recommend a 100x molar excess of the protein fragment control based on the concentration and the molecular weight. Pre-incubate the antibody-protein control fragment mixture for 30 min at room temperature.
IKIP (Inhibitor of nuclear factor kappa-B kinase-interacting protein, IKK-interacting protein) is a single-pass membrane protein that shares a common promoter with APAF1. APAF1 and IKIP are both induced by X irradiation, however, the two gene products are transcribed in different directions. The IKIP gene is believed to be a target for p53 as expression of IKIP has been shown to promote apoptosis. IKIP has four known isoforms, three of which are found traversing the endoplasmic reticulum membrane. IKIP isoform 4 has a deletion of the transmembrane region which leads to a homogenous distribution of the protein within the cell. The IKIP gene products are expressed in vascular endothelial cells, while the isoform 4 has also been detected in lung, kidney, spleen, thymus and skeletal muscle.- Environmental benefits include:
- Renewable Energy
Specifications
Q70UQ0 | |
Blocking Assay, Control | |
121457 | |
100 ÎĽL | |
1200009F10Rik; 1700023M03Rik; D18354; I kappa B kinase interacting protein; i kappa-B kinase interacting protein; i kappa-B kinase-interacting protein; Ikbip; IKBKB interacting protein; IKBKB-interacting protein; Ikip; IKK interacting protein; IKK-interacting protein; inhibitor of nuclear factor kappa-B kinase-interacting protein | |
IKBIP | |
Human | |
His-ABP-tag | |
-20°C, Avoid Freeze/Thaw Cycles | |
Liquid |
≥5.0 mg/mL | |
1 M urea, PBS with no preservative; pH 7.4 | |
Human IKBIP (aa 100-189) Control Fragment | |
RUO | |
IKBIP | |
Unconjugated | |
Recombinant | |
LESTESILQEATSSMSLMTQFEQEVSNLQDIMHDIQNNEEVLTQRMQSLNEKFQNITDFWKRSLEEMNINTDIFKSEAKHIHSQVTVQIN | |
E. coli | |
>80% by SDS-PAGE and Coomassie blue staining |