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Gibco™ Human GDF-3 Recombinant Protein, PeproTech®
Recombinant Protein
Supplier: Gibco™ LS120221MG
Description
Recombinant Human GDF-3 is a 26.0 kDa non-disulfide-linked homodimer containing two 114 amino acid polypeptide chains. This product is shipped at ambient temperature. For storage, handling and reconstitution information, please see the lot-specific Certificate of Analysis
GDF3 is a member of the bone morphogenetic protein (BMP) family and the TGF-beta superfamily. This group of proteins is characterized by a polybasic proteolytic processing site which is cleaved to produce a mature protein containing seven conserved cysteine residues. The members of this family are regulators of cell growth and differentiation in both embryonic and adult tissues. The function of this protein is unknown, but expression studies suggest it may be involved in regulation of the adult lymphatic and erythroid systems and embryonic development.Specifications
Q9NR23 | |
protein with no preservative | |
26 kDa | |
1 mg | |
RUO | |
C78318; ecat9; Gdf3; Gdf-3; growth differentiation factor 3; growth/differentiation factor 3; KFS3; MCOP7; MCOPCB6; RGD1564178; UNQ222/PRO248; VG-1-related protein 2; Vgr2; Vgr-2 | |
GDF3 | |
Unconjugated | |
AAIPVPKLSC KNLCHRHQLF INFRDLGWHK WIIAPKGFMA NYCHGECPFS LTISLNSSNY AFMQALMHAV DPEIPQAVCI PTKLSPISML YQDNNDNVIL RHYEDMVVDE CGCG | |
E. coli | |
≥ 98% by SDS-PAGE gel and HPLC analyses. |
ELISA, Functional Assay, Western Blot | |
9573 | |
Human GDF-3 | |
E. coli | |
<1 EU/ μg | |
GDF3 | |
Determined by its ability to inhibit induced alkaline phosphatase production by ATDC-5 chondrogenic cells. The ED50 for this effect is 100-150 ng/ml | |
Recombinant | |
-20°C | |
Lyophilized |