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Invitrogen™ Human CDKN2AIP (aa 82-160) Control Fragment Recombinant Protein
Recombinant Protein
Supplier: Invitrogen™ RP107135
Description
Highest antigen sequence indentity to the following orthologs: Mouse (90%), Rat (90%). This recombinant protein control fragment may be used for blocking experiments with the corresponding antibody, PA5-66460 (PA5-66460. In IHC/ICC and WB experiments, we recommend a 100x molar excess of the protein fragment control based on the concentration and the molecular weight. Pre-incubate the antibody-protein control fragment mixture for 30 min at room temperature.
CARF was first cloned as a novel binding partner of ARF from a yeast-interactive screen. CARF and ARF colocalize in the perinucleolar region and have a collaborative function. In the nucleoplasm, CARF interacts with p53 and enhances its function. The p53 downregulates CARF in a negative feedback regulatory loop and may also involve p53 antagonist HDM2.Specifications
Q9NXV6 | |
Blocking Assay, Control | |
55602 | |
100 ÎĽL | |
4921511I16Rik; AW208986; CARF; CDKN2A interacting protein; CDKN2A-interacting protein; CDKN2A-interacting protein-like protein; Cdkn2aip; CDKN2AIP-like protein; collaborates/cooperates with ARF (alternate reading frame) protein; collaborator of ARF; MGC137334 protein; RGD1305302 | |
Cdkn2aip | |
Human | |
His-ABP-tag | |
-20°C, Avoid Freeze/Thaw Cycles | |
Liquid |
≥5.0 mg/mL | |
1 M urea, PBS with no preservative; pH 7.4 | |
Human CDKN2AIP (aa 82-160) Control Fragment | |
RUO | |
CDKN2AIP | |
Unconjugated | |
Recombinant | |
WANHVFLGCRYPQKVMDKILSMAEGIKVTDAPTYTTRDELVAKVKKRGISSSNEGVEEPSKKRVIEGKNSSAVEQDHAK | |
E. coli | |
>80% by SDS-PAGE and Coomassie blue staining |