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Invitrogen™ Human CDKN2AIP (aa 82-160) Control Fragment Recombinant Protein

Recombinant Protein

Supplier:  Invitrogen™ RP107135

Catalog No. RP107135


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Description

Description

Highest antigen sequence indentity to the following orthologs: Mouse (90%), Rat (90%). This recombinant protein control fragment may be used for blocking experiments with the corresponding antibody, PA5-66460 (PA5-66460. In IHC/ICC and WB experiments, we recommend a 100x molar excess of the protein fragment control based on the concentration and the molecular weight. Pre-incubate the antibody-protein control fragment mixture for 30 min at room temperature.

CARF was first cloned as a novel binding partner of ARF from a yeast-interactive screen. CARF and ARF colocalize in the perinucleolar region and have a collaborative function. In the nucleoplasm, CARF interacts with p53 and enhances its function. The p53 downregulates CARF in a negative feedback regulatory loop and may also involve p53 antagonist HDM2.
Specifications

Specifications

Q9NXV6
Blocking Assay, Control
55602
100 ÎĽL
4921511I16Rik; AW208986; CARF; CDKN2A interacting protein; CDKN2A-interacting protein; CDKN2A-interacting protein-like protein; Cdkn2aip; CDKN2AIP-like protein; collaborates/cooperates with ARF (alternate reading frame) protein; collaborator of ARF; MGC137334 protein; RGD1305302
Cdkn2aip
Human
His-ABP-tag
-20°C, Avoid Freeze/Thaw Cycles
Liquid
≥5.0 mg/mL
1 M urea, PBS with no preservative; pH 7.4
Human CDKN2AIP (aa 82-160) Control Fragment
RUO
CDKN2AIP
Unconjugated
Recombinant
WANHVFLGCRYPQKVMDKILSMAEGIKVTDAPTYTTRDELVAKVKKRGISSSNEGVEEPSKKRVIEGKNSSAVEQDHAK
E. coli
>80% by SDS-PAGE and Coomassie blue staining
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