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runt-related transcription factor 3 (B01), Mouse anti-Human, Polyclonal Antibody, Abnova™
Mouse polyclonal antibody raised against a full-length human RUNX3 protein.
Supplier: Abnova Corporation H00000864B01
Description
This gene encodes a member of the runt domain-containing family of transcription factors. A heterodimer of this protein and a beta subunit forms a complex that binds to the core DNA sequence 5'-PYGPYGGT-3' found in a number of enhancers and promoters, and can either activate or suppress transcription. It also interacts with other transcription factors. It functions as a tumor suppressor, and the gene is frequently deleted or transcriptionally silenced in cancer. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq]
Sequence: MASNSIFDSFPTYSPTFIRDPSTSRRFTPPSPAFPCGGGGGKMGENSGALSAQAAVGPGGRARPEVRSMVDVLADHAGELVRTDSPNFLCSVLPSHWRCNKTLPVAFKVVALGDVPDGTVVTVMAGNDENYSAELRNASAVMKNQVARFNDLRFVGRSGRGKSFTLTITVFTNPTQVATYHRAIKVTVDGPREPRRHRQKLEDQTKPFPDRFGDLERLRMRVTPSTPSPRGSLSTTSHFSSQPQTPIQGTSELNPFSDPRQFDRSFPTLPTLTESRFPDPRMHYPGAMSAAFPYSATPSGTSISSLSVAGMPATSRFHHTYLPPPYPGAPQNQSGPFQANPSPYHLYYGTSSGSYQFSMVAGSSSGGDRSPTRMLASCTSSAASVAAGNLMNPSLGGQSDGVEADGSHSNSPTALSTPGRMDEAVWRPYSpecifications
runt-related transcription factor 3 | |
Polyclonal | |
Mouse polyclonal antibody raised against a full-length human RUNX3 protein. | |
RUNX3 | |
AML2/CBFA3/FLJ34510/MGC16070/PEBP2aC | |
Mouse | |
50 μL | |
Yes | |
864 | |
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing. |
Immunofluorescence, Immunohistochemistry (PFA fixed), Western Blot | |
Unconjugated | |
No additive | |
NM_001031680.2 | |
RUNX3 | |
RUNX3 (AAH13362.1, 1 a.a. ∼ 429 a.a) full-length human protein. | |
RUO | |
Primary | |
Human | |
Serum |