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glucosidase, beta; acid (includes glucosylceramidase), Mouse, Clone: 2E2, Abnova™
Mouse monoclonal antibody raised against a partial recombinant GBA.
Supplier: Abnova Corporation H00002629M01
Description
This gene encodes a lysosomal membrane protein that cleaves the beta-glucosidic linkage of glycosylceramide, an intermediate in glycolipid metabolism. Mutations in this gene cause Gaucher disease, a lysosomal storage disease characterized by an accumulation of glucocerebrosides. A related pseudogene is approximately 12kb downstream of this gene on chromosome 1. Alternative splicing results in multiple transcript variants encoding the same protein. [provided by RefSeq
Sequence: SYFSEEGIGYNIIRVPMASCDFSIRTYTYADTPDDFQLHNFSLPEEDTKLKIPLIHRALQLAQRPVSLLASPWTSPTWLKTNGAVNGKGSSpecifications
| glucosidase, beta; acid (includes glucosylceramidase) | |
| Monoclonal | |
| Unconjugated | |
| PBS with no preservative; pH 7.4 | |
| NM_000157 | |
| GBA | |
| GBA (NP_000148, 146 a.a. ∼ 235 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa. | |
| 100 μg | |
| Primary | |
| Human | |
| Antibody |
| ELISA, Immunofluorescence, Immunohistochemistry (PFA fixed), Western Blot | |
| 2E2 | |
| Mouse monoclonal antibody raised against a partial recombinant GBA. | |
| GBA | |
| GBA1/GCB/GLUC | |
| Mouse | |
| Affinity Purified | |
| RUO | |
| 2629 | |
| Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing. | |
| IgG2a κ |