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CDKN2B Monoclonal Antibody (DCS114.1), Invitrogen™
Mouse Monoclonal Antibody
Supplier: Thermo Fisher Scientific MA112294
Description
The four known 15-to 19 kDa INK4 proteins (p15INK4b, p16INK4a, p18INK4c andp19INK4d) bind and inhibit CDK4 and CDK6 but not other CDKs, including cyclin E-Cdk2, cyclin A-Cdk2 and cyclin B-Cdk1. Like the three D-type cyclins, the INK4 genes are expressed in distinct tissue-specific patterns, suggesting that they are not strictly redundant. 5 p18INK4c is expressed during G1 to S transition in the eukaryotic cell division cycle. It is maximally induced as cells enter S-phase.Specifications
| CDKN2B | |
| Monoclonal | |
| 1 mg/mL | |
| PBS with 0.08% sodium azide | |
| P42772 | |
| CDKN2B | |
| His-tagged recombinant full length p15 protein. | |
| 100 ÎĽg | |
| Primary | |
| Human | |
| Antibody | |
| IgG1 |
| Immunocytochemistry, Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot | |
| DCS114.1 | |
| Unconjugated | |
| CDKN2B | |
| AV083695; CDK inhibitory protein; CDK4B inhibitor; CDK4I; Cdkn2b; cyclin dependent kinase inhibitor 2B; Cyclin dependent kinase inhibitor 2B (p15, inhibits CDK4); cyclin-dependent kinase 4 inhibitor B; cyclin-dependent kinase inhibitor 2B (p15, inhibits CDK4); cyclin-dependent kinase inhibitor p15; cyclin-dependent kinase inhibitor p15INK4b; cyclin-dependent kinase inhibitor protein; cyclin-dependent kinases 4 and 6 binding protein; Ink4; INK4B; MTS2; MTS-2; Multiple tumor suppressor 2; p14_CDK inhibitor; p14_INK4B; p14-INK4b; P15; p15 CDK inhibitor; p15(INK4b); p15_INK4B; p15INK4b; p15-INK4b; TP15 | |
| Mouse | |
| Ammonium sulfate precipitation | |
| RUO | |
| 1030 | |
| -20° C, Avoid Freeze/Thaw Cycles | |
| Liquid |