Protease Inhibitors and Phosphatase Inhibitors
MilliporeSigma™ Calbiochem™ Ribonuclease Inhibitor, Human, Recombinant, E. coli
The Ribonuclease Inhibitor, Human, Recombinant, E. coli controls the biological activity of Ribonuclease. This small molecule/inhibitor is primarily used for Protease Inhibitors applications.
Thermo Scientific Chemicals Leupeptin, 90%, synthetic
CAS: 103476-89-7 Molecular Formula: 0·5 H2O4S
MilliporeSigma™ Calbiochem™ Cathepsin B Substrate III, Fluorogenic
Sensitive fluorogenic substrate for the quantitative determination of cathepsin B activity.
MilliporeSigma™ Calbiochem™ Sodium Orthovanadate, Activated
A depolymerized vanadate prepared from Sodium Orthovanadate with enhanced ability to competitively inhibit endogenous phosphatases.
Thermo Scientific™ Leupeptin Protease Inhibitor
Customize your protease inhibitor cocktail formulation with these small packages of individual protease inhibitor peptides and compounds.
MilliporeSigma™ Calbiochem™ Hydroxychloroquine Sulfate
A cell-permeable compound that increases intralysosomal pH and impairs autophagic degradation process. Suppresses proliferation of human dermal fibroblasts (IC50 = 30 μM).
MilliporeSigma™ Calbiochem™ HSP70 Inhibitor, PES-Cl
Directly binds to HSP70 and disrupts its interaction with client proteins..
MilliporeSigma™ Calbiochem™ Roscovitine
A potent, reversible, and selective inhibitor of Cdks that exhibits about 10-fold greater efficacy towards p34-cdk1 and p33-cdk2 and 20-fold greater efficacy towards p33-cdk5 relative to Olomoucine.
MilliporeSigma™ Calbiochem™ NAE Inhibitor, MLN4924
NAE Inhibitor, MLN4924, CAS 951950-33-7, is an AMP mimetic that forms a NAE-catalyzed NEDD8 adduct, which acts as a tight-binding, ATP-competitive NAE inhibitor (IC50 = 4.7nM).
MilliporeSigma™ Calbiochem™ Lactimidomycin
Lactimidomycin, CAS 134869-15-1, inhibits cell migration, proliferation, & protein synthesis (IC50 = 37.8nM). Blocks the first translocation step and has no effect on tRNA binding.
MilliporeSigma™ Calbiochem™ ACE2 Inhibitor, MLN-4760
A cell-permeable, highly potent inhibitor of angiotensin converting enzyme 2 (ACE2; IC50 = 440 pM).
![MilliporeSigma™ Calbiochem™ Forskolin, 7-Deacetyl-7-[O-(N-methylpiperazino)-γ-butyryl]-, Dihydrochloride](https://assets.fishersci.com/TFS-Assets/CCG/product-images/F584162~p.eps-250.jpg)
MilliporeSigma™ Calbiochem™ Forskolin, 7-Deacetyl-7-[O-(N-methylpiperazino)-γ-butyryl]-, Dihydrochloride
Chemically-modified forskolin with greater stability and water solubility than the parent compound.
MilliporeSigma™ Calbiochem™ Smoothened Agonist, SAG
A cell-permeable Smoothened Agonist, SAG, CAS 364590-63-6, modulates the coupling of Smo with its downstream effector by interacting with the Smo heptahelical domain (KD = 59 nM).
MilliporeSigma™ Calbiochem™ mTOR Inhibitor XI, Torin1
mTOR Inhibitor XI, Torin1, CAS 1222998-36-8, is a cell-permeable, highly potent, ATP-competitive inhibitor of mTOR and DNA-PK (IC50 = 4.32 and 6.34 nM, respectively).
MilliporeSigma™ Calbiochem™ MEK1/2 Inhibitor III
The MEK1/2 Inhibitor III, also referenced under CAS 391210-10-9, controls the biological activity of MEK1/2. This small molecule/inhibitor is primarily used for Phosphorylation & Dephosphorylation applications.