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Protein Modification Reagents

Chemical agents used to modify the amino acid side chains of proteins in order to alter their native charges, block or expose reactive binding sites, inactivate functional groups, and change functional groups to create targets for crosslinking and labeling.
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1 – 15 of 121 results
2

MilliporeSigma™ Calbiochem™ Coenzyme A, Trilithium Salt

Serves as cofactor in enzymatic acetyl transfer reactions

3

Thermo Scientific™ Pierce™ Iodoacetic Acid

Get rapid carboxymethylation of reduced cysteine residues with Thermo Scientific™ Pierce™ Iodoacetic Acid and Iodoacetamide.

4

Thermo Scientific™ MM(PEG)24 Methyl-PEG-Maleimide Reagent

Pegylate sulfhydryls (-SH groups) on proteins (cysteine residues) or assay surfaces using MS(PEG); sulfhydryl-reactive (maleimide), PEG compounds (12 and 24 EG units).

5

Thermo Scientific™ Pierce™ Premium Grade TCEP-HCl

Optimize applications where product integrity and risk minimization are paramount with our highest quality formulation of this disulfide reducing agent.

Content And Storage Upon receipt store product at room temperature in sealed container to prevent oxidation. Product is shipped at ambient temperature.
Product Type Disulfide Reducing Reagent
Product Line Pierce
7

MilliporeSigma™ Calbiochem TCEP, Neutral

Ready-to-use stable, neutral form of popular disulfide-reducing agent TCEP, Hydrochloride

8

MilliporeSigma™ Novagen™ Overnight Express™ Autoinduction System 2

Used for expression of proteins in multiple cultures.

Content And Storage Multiple storage requirements
10

MilliporeSigma™ Calbiochem™ Cleland’s Reagent, Molecular Biology Grade

Protective agent for SH groups

Content And Storage 2°C to 8°C
CAS 12-3-3483
Product Type Calbiochem Cleland’s Reagent
Form Crystalline Solid
Molecular Weight (g/mol) 154.24
Solubility EtOH, Water
Purity ≥99% by titration
Synonym 1,4-Dithiothreitol, DTT
Molecular Formula C4H10O2S2
11

Thermo Scientific™ Immobilized Pepsin (Agarose Resin)

Generate and purify Fab and F(ab')2 fragments from antibodies with acidic endopeptidase (pepsin) immobilized onto beaded agarose resin.

12

Thermo Scientific™ Pierce™ Sodium meta-Periodate

Gently oxidize glycoprotein carbohydrate sugars to create reactive aldehydes (carbonyls) for crosslinking and immobilization using NaIO4 (CAS 7790-28-5).