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Protein Modification Reagents

Chemical agents used to modify the amino acid side chains of proteins in order to alter their native charges, block or expose reactive binding sites, inactivate functional groups, and change functional groups to create targets for crosslinking and labeling.
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1 – 15 of 121 results
1

Invitrogen™ Measure-IT™ Thiol Assay Kit  DFS Item

Provides easy and accurate quantitation of thiol

2

Thermo Scientific™ Pierce™ HRV 3C Protease Solution Kit (2 units/μL)

Remove fusion tags from proteins with the HRV 3C cleavage sequence with this recombinant cysteine protease that is dual tagged for easy removal from the sample after cleavage.

Content And Storage Store at -20°C.
Product Type Protease
Form Kit
Product Line Pierce
3

Thermo Scientific™ MS(PEG)12 Methyl-PEG-NHS-Ester Reagent

Pegylate amines (-NH2 groups) on proteins (lysine residues) or assay surfaces using MS(PEG)n, amine-reactive (NHS ester), methyl-capped PEG compounds (4 to 24 EG units).

Content And Storage Store desiccated at -20°C.
Product Type NHS-Ester Reagent
Spacer 12 ethylene glycol units
Solubility Water
Reactive Moiety Active Ester, Succinimidyl Ester, NHS Ester
Label Type Polyethylene Glycol (PEG), Blocking Groups
Chemical Reactivity Amine
4

Thermo Scientific™ MM(PEG)24 Methyl-PEG-Maleimide Reagent

Pegylate sulfhydryls (-SH groups) on proteins (cysteine residues) or assay surfaces using MS(PEG); sulfhydryl-reactive (maleimide), PEG compounds (12 and 24 EG units).

5

Thermo Scientific™ Pierce™ NEM (N-ethylmaleimide)

Small, sulfhydryl-reactive (maleimide) compound to permanently block reduced cysteines of proteins or peptides to prevent disulfide bond formation.

6

Thermo Scientific™ Pierce™ TCEP-HCl, No-Weigh™ Format

Reduce protein and peptide disulfide bonds using this thiol-free, pure, crystalline tris (2-carboxyethyl) phosphine hydrochloride, TCEP (CAS 5961-85-3).

Form Solid
7

MilliporeSigma™ Proteinase K, Lyophilized

Highly active serine protease that exhibits broad cleavage specificity on native and denatured proteins and is widely used in the purification of DNA and RNA

Content And Storage 2°C to 8°C
CAS 39450-01-6
Product Type Proteinase K
9

MilliporeSigma™ Calbiochem™ Cleland’s Reagent, Molecular Biology Grade

Protective agent for SH groups

Content And Storage 2°C to 8°C
CAS 12-3-3483
Product Type Calbiochem Cleland’s Reagent
Form Crystalline Solid
Molecular Weight (g/mol) 154.24
Solubility EtOH, Water
Purity ≥99% by titration
Synonym 1,4-Dithiothreitol, DTT
Molecular Formula C4H10O2S2
11

Thermo Scientific™ Pierce™ Immobilized Reductant Column, 2 mL

Efficiently reduce protein or peptide disulfide bonds with this reusable column on with an immobilized thiol-based reducing agent for solid-phase disulfide bond reduction.

12

Thermo Scientific™ CA(PEG)4 Carboxy-PEG-Amine Compound

CA(PEG)n: pegylated amino acids of the form carboxy-PEG-amine; with 4 to 24 polyethylene glycol units; for surface- and molecule-pegylation applications.

Content And Storage Store desiccated at 4°C. Shipped at ambient temperature.
Product Type Amine Compound
Spacer 4 ethylene glycol units
Solubility Water
Reactive Moiety Amine, Carboxylic Acid, Primary Amine
Label Type Conjugating Groups, Polyethylene Glycol (PEG)
13

Thermo Scientific™ MT(PEG)4 Methyl-PEG-Thiol Compound

MT(PEG)n: methyl and sulfhydryl compound with a 4-unit polyethylene glycol (PEG) spacer; methylate and pegylate quantum dots, gold surfaces, silver.

14

Thermo Scientific™ CT(PEG)12 Carboxy-PEG-Thiol Compound

CT(PEG)n: carboxylic acid and sulfhydryl compound with a 12-unit polyethylene glycol (PEG) spacer; carboxylate and pegylate quantum dots, gold surfaces, silver.

15

Thermo Scientific™ Proteinase K Powder (≥30 U/mg)

Cleave at the carboxyl-side of aliphatic, aromatic or hydrophobic residues and digest-inactivate DNase and RNase in nucleic acid purification using this protease.