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Thermo Scientific™ MT(PEG)4 Methyl-PEG-Thiol Compound

Catalog No. PI26132
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100 mg
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PI26132 100 mg
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Catalog No. PI26132 Supplier Thermo Scientific™ Supplier No. 26132
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Description

MT(PEG)n: methyl and sulfhydryl compound with a 4-unit polyethylene glycol (PEG) spacer; methylate and pegylate quantum dots, gold surfaces, silver.

Thermo Scientific™ Pierce MT(PEG)4, or methyl-PEG4-thiol, is a methyl- and sulfhydryl-terminated compound that contains a 4-unit polyethylene glycol (PEG) spacer and is used to modify surfaces such as quantum dots, monolayers and magnetic particles.

MT(PEG)4 is monodentate thiol-terminated and methyl pegylation reagent. The PEG compound has a defined molecular weight and spacer length and is useful for modifying surfaces such quantum dots, self-assembled monolayers and magnetic particles. Functionalization of solid surfaces with polyethylene glycol spacers such as this one significantly reduces nonspecific protein binding.

Highlights:

  • Metal-binding – terminal monodentate thiol reacts spontaneously with gold surfaces through dative binding

  • Methyl – terminal methyl group is unreactive, the primary function of this compound being to coat quantum dot and other surfaces to reduce nonspecific binding in assays

  • Polyethylene glycol – PEG groups are flexible, non-immunogenic, hydrophilic, and significantly reduce nonspecific binding of surfaces for protein methods

  • Spacer arm – four-unit PEG spacer makes compound nearly 16 angstroms long

Specifications:

  • Alternative name: Methyl-PEG4-Thiol
  • Chemical name: 2,5,8,11-tetraoxatridecane-13-thiol
  • Chemical formula: C9H20O4S
  • Molecular weight: 224.32
  • Spacer arm: 15.8 angstroms
  • Form: clear colorless to light yellow liquid
  • Solubility: dissolve in DMSO or DMF for use

Specifications

Chemical Reactivity Metal Surface
Content And Storage Upon receipt store at -20°C protected from moisture. Products shipped at ambient temperature.
Label Type Polyethylene Glycol (PEG), Blocking Groups
Reactive Moiety Carboxylic Acid, Thiol
Spacer 4 ethylene glycol units
Form Liquid
Quantity 100 mg
Solubility DMF or DMSO
Product Type Thiol Compound

Frequently Asked Questions (FAQs)

What are the recommended storage conditions for MT(PEG)4 Methyl-PEG-Thiol Compound (Cat. No. 26132)?

MT(PEG)4 Methyl-PEG-Thiol Compound (Cat. No. 26132) turns to liquid at RT. PEG-thiol reagents are low-melting solids that are difficult to weigh and dispense. To facilitate handling, make a stock solution by dissolving the entire contents of the bottle (100 mg in solid or liquid form) in dimethylsulfoxide (DMS) or dimethylformamide (DMF) to the desired stock concentration. Store unused stock solution at -20 degrees C.

Please note: the molecular weight of MT(PEG)4 Methyl-PEG-Thiol Compound is 224.32 g/ml.

For more information about protocol an use, please refer to the Instructions.
I received my order of MT(PEG)4 Methyl-PEG-Thiol Compound (Cat. No. 26132) as a liquid solution, instead of a solid form. Is this normal?

MT(PEG)4 Methyl-PEG-Thiol Compound (Cat. No. 26132) turns to liquid at RT. It is normal for the product to change state during transport as it is shipped at ambient temperature. The PEG-thiol reagents are low-melting solids that are difficult to weigh and dispense. To facilitate handling, make a stock solution by dissolving the entire contents of the bottle (100 mg in solid or liquid form) in dimethylsulfoxide (DMS) or dimethylformamide (DMF) to the desired stock concentration. Store unused stock solution at -20 degrees C.

Please note: the molecular weight of MT(PEG)4 Methyl-PEG-Thiol Compound is 224.32 g/ml.

For more information about protocol and use, please refer to the Instructions.

For Research Use Only. Not for use in diagnostic procedures.