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Thermo Scientific™ MT(PEG)4 Methyl-PEG-Thiol Compound

Catalog No. PI26132
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100 mg
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PI26132 100 mg
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Catalog No. PI26132 Supplier Thermo Scientific™ Supplier No. 26132
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Description

MT(PEG)n: methyl and sulfhydryl compound with a 4-unit polyethylene glycol (PEG) spacer; methylate and pegylate quantum dots, gold surfaces, silver.

Thermo Scientific™ Pierce MT(PEG)4, or methyl-PEG4-thiol, is a methyl- and sulfhydryl-terminated compound that contains a 4-unit polyethylene glycol (PEG) spacer and is used to modify surfaces such as quantum dots, monolayers and magnetic particles.

MT(PEG)4 is monodentate thiol-terminated and methyl pegylation reagent. The PEG compound has a defined molecular weight and spacer length and is useful for modifying surfaces such quantum dots, self-assembled monolayers and magnetic particles. Functionalization of solid surfaces with polyethylene glycol spacers such as this one significantly reduces nonspecific protein binding.

Highlights:

  • Metal-binding – terminal monodentate thiol reacts spontaneously with gold surfaces through dative binding

  • Methyl – terminal methyl group is unreactive, the primary function of this compound being to coat quantum dot and other surfaces to reduce nonspecific binding in assays

  • Polyethylene glycol – PEG groups are flexible, non-immunogenic, hydrophilic, and significantly reduce nonspecific binding of surfaces for protein methods

  • Spacer arm – four-unit PEG spacer makes compound nearly 16 angstroms long

Specifications:

  • Alternative name: Methyl-PEG4-Thiol
  • Chemical name: 2,5,8,11-tetraoxatridecane-13-thiol
  • Chemical formula: C9H20O4S
  • Molecular weight: 224.32
  • Spacer arm: 15.8 angstroms
  • Form: clear colorless to light yellow liquid
  • Solubility: dissolve in DMSO or DMF for use

Specifications

Chemical Reactivity Metal Surface
Content And Storage Upon receipt store at -20°C protected from moisture. Products shipped at ambient temperature.
Label Type Polyethylene Glycol (PEG), Blocking Groups
Reactive Moiety Carboxylic Acid, Thiol
Spacer 4 ethylene glycol units
Form Liquid
Quantity 100 mg
Solubility DMF or DMSO
Product Type Thiol Compound

For Research Use Only. Not for use in diagnostic procedures.