Cocktails, tablets, capsules, and individual purified formulations of protease inhibitors and phosphatase inhibitors designed to protect proteins from degradation during cell lysis and extraction.
Lactate Dehydrogenase A Inhibitor, FX11, CAS 213971-34-7, is a cell permeable, selective, reversible, NADH competitive inhibitor of lactate dehhydrogenase A (LDHA; Ki = 8μM for human liver LDHA).
A cell-permeable, orally bioavailable, blood-brain barrier-permeant MTIC [5-(3-methyltriazen-1-yl-)-imidazole-4-carboxamide] prodrug whose in vivo DNA alkylating activity is employed in anticancer ther
PP2, CAS 172889-27-9, is a potent, reversible, ATP-competitive, inhibitor of the Src family of protein tyrosine kinases (IC50 = 4, 5, 5, & 100 nM for p56lck, p59fynT, Hck, & Src, respectively).
A cell-permeable, potent, non-toxic, inverse agonist of RORγt. Directly and reversibly interacts with the ligand binding domain of RORγt to block its transcriptional effects.
The Protease Inhibitor Cocktail Set VI controls the activity of Protease. This small molecule/inhibitor is primarily used for Protease Inhibitors applications.
Rho Inhibitor, Rhosin, CAS 1173671-63-0, is a cell-permeable compound that directly targets Rho GEF binding domain (Kd = 354nM for RhoA), thereby prevents Rho from interacting with its GEFs.
The Dynamin Inhibitor II, MiTMAB, also referenced under CAS 1119-97-7, controls the biological activity of Dynamin. This small molecule/inhibitor is primarily used for Membrane applications.