Protein Modification Reagents

MilliporeSigma™ Calbiochem™ Sorbitol

Produced by reduction of glucose

MilliporeSigma™ Endoproteinase Glu-C, Excision Grade, Staphylococcus aureus

Serine protease that specifically hydrolyzes peptide bonds at carboxylic side of glutamic acid and aspartic acid residues

Thermo Scientific™ MM(PEG)24 Methyl-PEG-Maleimide Reagent

Pegylate sulfhydryls (-SH groups) on proteins (cysteine residues) or assay surfaces using MS(PEG); sulfhydryl-reactive (maleimide), PEG compounds (12 and 24 EG units).

2-Mercaptoethanol, For HPLC derivatization (14.3 M), ≥99.0% (GC), MilliporeSigma™ Supelco™

Thermo Scientific™ Trypsin, TPCK Treated

Thermo Scientific Pierce TPCK Trypsin is a serine endoprotease that is applicable to amino acid analysis and protein sequencing, mapping and structural studies; the immobilized form allows sample separation after treatment.

MilliporeSigma™ Calbiochem TCEP, Neutral

Ready-to-use stable, neutral form of popular disulfide-reducing agent TCEP, Hydrochloride

Thermo Scientific™ Pierce™ DTT (Dithiothreitol)

Reduce disulfides in biological buffers and sample loading buffers with pure, crystalline dithiothreitol (DTT), the most popular protein disulfide reducing agent.

Thermo Scientific™ CA(PEG)24 Carboxy-PEG-Amine Compound

CA(PEG)n: pegylated amino acids of the form carboxy-PEG-amine; with 4 to 24 polyethylene glycol units; for surface- and molecule-pegylation applications.

MilliporeSigma™ Aminopeptidase N, Rat

Levels of aminopeptidase N are elevated in cancer subjects and correlate with tumor load, and thus, enzyme is believed to play role in angiogenesis

MilliporeSigma™ Aminopeptidase N (CD13), Human Serum

Prepared from human serum that has been shown by certified tests to be negative for HBsAg and for antibodies to HIV and HCV

MilliporeSigma™ Calbiochem™ TPEN

Lipid-soluble heavy metal chelator that crosses artificial and natural membranes

Invitrogen™ DTNB; Ellman's Reagent, 5,5'-Dithiobis-(2-Nitrobenzoic Acid)  

DTNB; Ellman's Reagent, 5,5'-Dithiobis-(2-Nitrobenzoic Acid)

MilliporeSigma™ Calbiochem™ 5'-Deoxy-5'-methylthioadenosine

Inhibits protein carboxymethyltransferase, induces apoptosis in leukemia U937 cells.

Thermo Scientific™ Pierce™ Alkylating Reagents

Alkylating reagents provided in single-use, pre-weighed formats to streamline protein preparation workflows.

Thermo Scientific™ Pierce™ TCEP-HCl, No-Weigh™ Format

Reduce protein and peptide disulfide bonds using this thiol-free, pure, crystalline tris (2-carboxyethyl) phosphine hydrochloride, TCEP (CAS 5961-85-3).