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HPLC Guard Columns and Cartridges

Replaceable columns that are placed before HPLC columns to protect from contamination and extend column lifetime; in a variety of stationary phases; includes direct-connection and drop-in cartridges, and UHPLC filters, cartridges, and holders.
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1
Promotions Available

Thermo Scientific™ Hypersil GOLD™ Javelin™ Guard Columns

Offer convenient, easy to use protection for analytical HPLC columns

Stationary Phase C18
Length (Metric) 10 mm
2

MilliporeSigma™ Supelco™ SUPELCOGEL™ H Guard Column, 9 μm Particle Size

SUPELCOGEL™ H Guard Column is used for the protection of SUPELCOGEL™ Ion Exclusion Columns.

3

MilliporeSigma™ Supelco™ SUPELCOGEL™ K Guard Column, 9 μm Particle Size

5 cm x 4.6 mm guard column, does not include tubing, nuts or ferrules.

4

MilliporeSigma™ Supelco™ SUPELCOSIL™ LC-DP Supelguard Cartridge, 5 μm Particle Size

Contains a diphenyl bonded phase, which gives greater selectivity for aromatic groups compared to alkyl-type bonded phases.

5

MilliporeSigma™ Supelco™ SUPELCOSIL™ LC-1 Supelguard Cartridge, 5 μm Particle Size

Due to a mixed retention mechanism, selectivity differences for polar groups are more pronounced than on C8 and C18 columns. C1 columns require 20-30% less organic modifier to provide retention similar to C18 columns.

6

MilliporeSigma™ Supelco™ SRT™-C SEC-100 Gel Filtration Guard Column, 5 μm Particle Size, PEEK

The bonded phase in SRT™-C SEC columns is more polar than the hydrophilic phase used in SRT™ columns, making SRT™-C columns better suited for the gel filtration analysis of more hydrophobic bioopolymers such as membrane proteins and pegylated antibodies.

7

MilliporeSigma™ Supelco™ SRT™ SEC-1000 Gel Filtration Guard Column, 5 μm Particle Size, PEEK

Sepax SRT™ SEC columns feature a hydrophilic surface layer that effectively shields the highly porous, five micron silica particles from interacting with your sample.

8

MilliporeSigma™ Supelco™ Proteomix™ WCX-NP3 Weak Cation Exchange Guard Cartridge and Holder, 3 μm Particle Size, Stainless Steel

Used for the analysis or small scale purification of positively charged biopolymers including glycoprotein isoforms and mAb variants.

Pore Size Non-porous
Particle Size 3 μm
Type Cation Exchange HPLC Guard Cartridge and Holder
Phase Cation Exchange
Length (Metric) 1 cm
pH 2.0 to 12.0
Material Stainless Steel
For Use With (Application) HPLC
Product Line Proteomix
9

MilliporeSigma™ Supelco™ Ascentis™ Express RP-Amide Guard Cartridge, 5 μm Particle Size

Ascentis™ Express Guard Columns provide physical (filtration) and chemical protection for costly analytical columns without compromising the very high performance of Ascentis™ Express columns.

Pore Size 90 Å
Particle Size 5 μm
Type Fused-Core HPLC Guard Cartridge
Phase Reversed Phase
Length (Metric) 5 mm
Quantity 3/Pk.
For Use With (Application) HPLC
Product Line Ascentis
10

MilliporeSigma™ Supelco™ Ascentis™ Express F5 Guard Cartridge, 2 μm Particle Size

Ascentis™ Express Guard Columns provide physical (filtration) and chemical protection for costly analytical columns without compromising the very high performance of Ascentis™ Express columns.

Particle Size 2 μm
Type Fused-Core HPLC Guard Cartridge
Phase Reversed Phase and HILIC
Length (Metric) 5 mm
Quantity 3/Pk.
For Use With (Application) HPLC
Product Line Ascentis
11

MilliporeSigma™ Supelco™ Ascentis™ Express HILIC Guard Cartridge, 2 μm Particle Size

Ascentis™ Express Guard Columns provide physical (filtration) and chemical protection for costly analytical columns without compromising the very high performance of Ascentis™ Express columns.

Pore Size 90 Å
Particle Size 2 μm
Type Fused-Core HPLC Guard Cartridge
Phase HILIC
Length (Metric) 5 mm
Quantity 3/Pk.
For Use With (Application) HPLC
Product Line Ascentis
12

MilliporeSigma™ Supelco™ Ascentis™ Express ES-Cyano Guard Cartridge, 2.7 μm Particle Size

Ascentis™ Express Guard Columns provide physical (filtration) and chemical protection for costly analytical columns without compromising the very high performance of Ascentis™ Express columns.

Pore Size 90 Å
Particle Size 2.7 μm
Type Fused-Core HPLC Guard Cartridge
Phase Reversed Phase, Normal Phase, HILIC
Length (Metric) 5 mm
Quantity 3/Pk.
For Use With (Application) HPLC
Product Line Ascentis
13

MilliporeSigma™ Supelco™ Ascentis™ Express RP-Amide Guard Cartridge, 2.7 μm Particle Size

Ascentis™ Express Guard Columns provide physical (filtration) and chemical protection for costly analytical columns without compromising the very high performance of Ascentis™ Express columns.

Pore Size 90 Å
Particle Size 2.7 μm
Type Fused-Core HPLC Guard Cartridge
Phase Reversed Phase
Length (Metric) 5 mm
Quantity 3/Pk.
For Use With (Application) HPLC
Product Line Ascentis
14

TSKgel™ Boronate-5PW HPLC Guardgel Kit, Sold by MilliporeSigma™ Supelco™

Boronate-5PW HPLC guardgel kit

Particle Size 20 μm
Stationary Phase M-aminophenyl boronate phase
pH 2 to 9
Technique Affinity
Column Capacity 40 μmol/mL, resin adsorption capacity (sorbitol)
15

TSKgel™ GMHHR-H(S) Guard Column, 13 μm Particle Size, Sold by MilliporeSigma™ Supelco™

Guard Column for use with TSKgel™ GMHHR-H(S) HPLC Columns (817361). TSKgel™ GMHHR-H mixed bed columns are packed with rigid, multiple pore size, polymer beads.