Protease Inhibitors and Phosphatase Inhibitors
MilliporeSigma™ Calbiochem™ Arp2/3 Complex Inhibitor I, CK-666
The Arp2/3 Complex Inhibitor I, CK-666, also referenced under CAS 442633-00-3, controls the biological activity of Arp2/3. This small molecule/inhibitor is primarily used for Cell Structure applications.
MilliporeSigma™ Calbiochem™ InSolution™ Tamoxifen, 4-Hydroxy-, (Z)-
A 10 mM (2 mg/516 μL) sterile-filtered solution of (Z)-4-Hydroxytamoxifen in ethanol.
MilliporeSigma™ Calbiochem™ InSolution™ Cyclopamine-KAAD
A cell-permeable potent analog of Cyclopamine that specifically inhibits Hedgehog (Hh) signaling with similar or lower toxicity.
MilliporeSigma™ Calbiochem™ Cyclopamine, V. californicum
Cyclopamine, V. californicum, CAS 4449-51-8, is a cell-permeable steroidal alkaloid & cholesterol mimic that specifically antagonizes Sonic Hedgehog signaling through direct interaction with Smo.
MilliporeSigma™ Calbiochem™ α-Amyloid Precursor Protein Modulator
A cell-permeable benzolactam derived PKC activator (K
MilliporeSigma™ Calbiochem™ InSolution™ Smoothened Agonist, SAG
InSolution™ Smoothened Agonist, SAG, is a 10 mM (500 μg/86 μl) solution of Smoothened Agonist, SAG (Cat. No. 566660) in H2O.
MilliporeSigma™ Calbiochem™ STAT3 Inhibitor III, WP1066
STAT3 Inhibitor III, WP1066, CAS 857064-38-1, is a cell-permeable AG490 tyrphostin analog that acts as a STAT3 pathway inhibitor. A potent anti-tumor agent.
MilliporeSigma™ Calbiochem™ STAT5 Inhibitor III, Pimozide
The STAT5 Inhibitor III, Pimozide, also referenced under CAS 2062-78-4, controls the biological activity of STAT5.
MilliporeSigma™ Calbiochem™ Purmorphamine
A cell-permeable activator of Hedgehog signaling that induces osteoblast differentiation of multipotent mesenchymal progenitor cells C3H10T1/2 (EC50 = 1 μM).
Thermo Scientific Chemicals Leupeptin Hemisulfate
CAS: 103476-89-7 Molecular Formula: C20H39N6O4+
MilliporeSigma™ Calbiochem™ Protease Inhibitor Cocktail Set III, Animal-Free
Protease Inhibitor Cocktail Set III, Animal-Free, is a cocktail of six protease inhibitors with broad specificity for the inhibition of aspartic, cysteine & serine proteases & aminopeptidases.
MilliporeSigma™ Calbiochem™ AG 490
A cell-permeable, reversible, substrate competitive, and potent inhibitor of epidermal growth factor receptor kinase autophosphorylation (IC50 = 100 nM).
MilliporeSigma™ Calbiochem™ InSolution™ Nocodazole
Inhibitor of mitosis. Has highly specific antimicrotubular activity for mammalian cells in culture.
MilliporeSigma™ Calbiochem™ Forskolin, Coleus forskohlii
Forskolin, CAS 66575-29-9, is a cell-permeable diterpene inotropic agent that acts as an activator of adenylate cyclase (EC50 = 4 mM).