Protease Inhibitors and Phosphatase Inhibitors
MilliporeSigma™ Calbiochem™ 2-APB
A cell-permeable modulator of Ins(1,4,5)P3-induced Ca2+ release.
MilliporeSigma™ Calbiochem™ D,L-Sulforaphane
An isothiocyanate isolated from broccoli that acts as a potent inducer of phase II detoxifying enzymes in mouse tissues and murine hepatoma cells in culture.
MilliporeSigma™ Calbiochem™ GSK-3 Inhibitor XVI
GSK-3 Inhibitor XVI - CAS 252917-06-9, is a cell-permeable, potent, ATP-competitive, and highly selective GSK-3 inhibitor (IC50 = 10 and 6.7 nM against GSK-3α and GSK-3β, respectively).
MilliporeSigma™ Calbiochem™ Berberine Chloride
A highly potent and selective oxysterol EBI2 (GPR183) agonist (K
MilliporeSigma™ Calbiochem™ (-)-Blebbistatin
The active enantiomer of (±)-Blebbistatin that accounts for the inhibitory activity towards ATPase and myosin II-dependent cellular processes.
MilliporeSigma™ Calbiochem™ (±)-Blebbistatin
(±)-Blebbistatin, CAS 674289-55-5, is a cell-permeable, selective, and reversible inhibitor of nonmuscle myosin II. Blocks cell blebbing and disrupts cell migration & cytoKinesis in vertebrate cells.
MilliporeSigma™ Calbiochem™ CA-074 Me
CA-074 Me, CAS 147859-80-1, is a cell-permeable analog of CA-074 that acts as an irreversible inhibitor of intracellular cathepsin B.
MilliporeSigma™ Calbiochem™ Protease Inhibitor Cocktail Set VII
Protease Inhibitor Cocktail Set VII contains five protease inhibitors with broad specificity. Recommended for purification of proteins containing His·Tag™ sequences.
MilliporeSigma™ Calbiochem™ α-Amyloid Precursor Protein Modulator
A cell-permeable benzolactam derived PKC activator (K
MilliporeSigma™ Calbiochem™ InSolution™ Smoothened Agonist, SAG
InSolution™ Smoothened Agonist, SAG, is a 10 mM (500 μg/86 μl) solution of Smoothened Agonist, SAG (Cat. No. 566660) in H2O.
MilliporeSigma™ Calbiochem™ InSolution™ GSK-3 Inhibitor XVI, CHIR99021
InSolution™ GSK-3 Inhibitor XVI, CHIR99021, CAS 252917-06-9, is a 25 mM solution in DMSO. A cell-permeable, ATP-competitive inhibitor of GSK-3 (IC50 = 10 & 6.7 nM for GSK-3α and GSK-3β, respectively).
MilliporeSigma™ Calbiochem™ InSolution™ Jasplakinolide, Jaspis johnstoni
InSolution™ Jasplakinolide, Jaspis johnstoni, CAS 102396-24-7, is a 1mm solution of Jasplakinolide, Jaspis johnstoni in DMSO. Acts as a potent inducer of actin polymerization and stabilization.
MilliporeSigma™ Calbiochem™ MMP-12 Inhibitor, MMP408
The MMP-12 Inhibitor, MMP408, also referenced under CAS 1258003-93-8, controls the biological activity of MMP-12. This small molecule/inhibitor is primarily used for Protease Inhibitors applications.
MilliporeSigma™ Calbiochem™ 5-Lipoxygenase Inhibitor, MK591
MK591; MK0591; 5-LOX inhibitor, 5- Lipoxygenase inhibitor, FLAP