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Protein Modification Reagents

Chemical agents used to modify the amino acid side chains of proteins in order to alter their native charges, block or expose reactive binding sites, inactivate functional groups, and change functional groups to create targets for crosslinking and labeling.
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1 – 15 of 121 results
1

MilliporeSigma™ Calbiochem™ Caffeic Acid

Reported to have anti-carcinogenic anti-inflammatory properties.

2

Thermo Scientific™ Pierce™ SAT(PEG)4 (PEGylated N-succinimidyl S-acetylthioacetate)

Long (18.2A), pegylated form of SATA, an amine-reactive (NHS ester) sulfhydryl-addition reagent; contains 4-unit polyethylene glycol spacer arm.

4

MilliporeSigma™ Calbiochem™ 5'-Deoxy-5'-methylthioadenosine

Inhibits protein carboxymethyltransferase, induces apoptosis in leukemia U937 cells.

6

Thermo Scientific™ CA(PEG)4 Carboxy-PEG-Amine Compound

CA(PEG)n: pegylated amino acids of the form carboxy-PEG-amine; with 4 to 24 polyethylene glycol units; for surface- and molecule-pegylation applications.

Content And Storage Store desiccated at 4°C. Shipped at ambient temperature.
Product Type Amine Compound
Spacer 4 ethylene glycol units
Solubility Water
Reactive Moiety Amine, Carboxylic Acid, Primary Amine
Label Type Conjugating Groups, Polyethylene Glycol (PEG)
8

Thermo Scientific™ Immobilized Pepsin (Agarose Resin)

Generate and purify Fab and F(ab')2 fragments from antibodies with acidic endopeptidase (pepsin) immobilized onto beaded agarose resin.

9

Thermo Scientific™ Pierce™ Sodium meta-Periodate

Gently oxidize glycoprotein carbohydrate sugars to create reactive aldehydes (carbonyls) for crosslinking and immobilization using NaIO4 (CAS 7790-28-5).

10

MilliporeSigma™ Calbiochem™ BAPTA/AM

Can be loaded into wide variety of cells, where it is hydrolyzed by cytosolic esterases and is trapped intracellularly as the active chelator BAPTA

Membrane Permeable Y
Content And Storage -20°C
CAS 126150-97-8
Product Type Calbiochem BAPTA/AM
Form Solid
Solubility DMSO
Purity ≥90% by TLC
Synonym 1,2-bis(o-Aminophenoxy)ethane-N,N,Nʹ,Nʹ-tetraacetic Acid Tetra(acetoxymethyl) Ester
11

Thermo Scientific™ Immobilized Ficin (Agarose Resin)

Enable controlled antibody fragmentation, especially of mouse IgG1, with this sulfhydryl-specific ficin protease immobilized onto beaded agarose resin.

13

MilliporeSigma™ Calbiochem™ TPEN

Lipid-soluble heavy metal chelator that crosses artificial and natural membranes

14

Thermo Scientific™ Pierce™ Premium Grade TCEP-HCl

Optimize applications where product integrity and risk minimization are paramount with our highest quality formulation of this disulfide reducing agent.

Content And Storage Upon receipt store product at room temperature in sealed container to prevent oxidation. Product is shipped at ambient temperature.
Product Type Disulfide Reducing Reagent
Product Line Pierce