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Thermo Scientific™ Pierce™ DTT (Dithiothreitol)

Reduce disulfides in biological buffers and sample loading buffers with pure, crystalline dithiothreitol (DTT), the most popular protein disulfide reducing agent.

Manufacturer: thermo scientific™  20290

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Catalog No. PI20290


Description & Specifications


Description Pierce DTT, Cleland's Reagent
Formulation Pure (approx. 98%) white powder of dithiothreitol
Quantity 5g
Sufficient For Preparing 64.8mL of 0.5M solution

Thermo Scientific™ Pierce DTT (Dithiothreitol) is offered as 7.7mg × 48-tube microplates for convenient preparation of 100μL of 0.5M stocks for addition to protein samples for effective reduction of disulfide bonds.


  • A water-soluble reagent that reduces disulfide bonds
  • Maintains mono-thiols completely in the reduced state and reduces disulfide bonds quantitatively
  • Specific and sensitive assay for disulfides using DTT with Ellman's Reagent