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Protein Modification Reagents

Chemical agents used to modify the amino acid side chains of proteins in order to alter their native charges, block or expose reactive binding sites, inactivate functional groups, and change functional groups to create targets for crosslinking and labeling.
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1 – 15 of 122 results
2

Thermo Scientific™ Immobilized Pepsin (Agarose Resin)

Generate and purify Fab and F(ab')2 fragments from antibodies with acidic endopeptidase (pepsin) immobilized onto beaded agarose resin.

3

Thermo Scientific™ Pierce™ Sodium meta-Periodate

Gently oxidize glycoprotein carbohydrate sugars to create reactive aldehydes (carbonyls) for crosslinking and immobilization using NaIO4 (CAS 7790-28-5).

4

Thermo Scientific™ Pierce™ Hydroxylamine-HCl

NH2OH (CAS 7803-49-8) to cleave Asn-Gly peptide bonds or deprotect sulfhydryls following S-acetylthioacetate modification with SATA reagent.

5

MilliporeSigma™ Aminopeptidase N, Rat

Levels of aminopeptidase N are elevated in cancer subjects and correlate with tumor load, and thus, enzyme is believed to play role in angiogenesis

6

MilliporeSigma™ Aminopeptidase N (CD13), Human Serum

Prepared from human serum that has been shown by certified tests to be negative for HBsAg and for antibodies to HIV and HCV

7

MilliporeSigma™ Calbiochem™ TPEN

Lipid-soluble heavy metal chelator that crosses artificial and natural membranes

8

Thermo Scientific Chemicals Papain, Carica Papaya Latex

CAS: 9001-73-4 Synonym: EC 3.4.22.2

CAS 9001-73-4
Synonym EC 3.4.22.2
9

MilliporeSigma™ Calbiochem™ Sialyl Lewis x, Sodium Salt

Acts as minimal binding lig for E-selectins.

Content And Storage -20°C
10

Invitrogen™ Protease QF

Protease QF, 180 μL, is an enzyme in aqueous buffered solution and an individual component of the ViewRNA™ ISH Tissue Assay Kits, 2-Plex, 24 assays.

11

Thermo Scientific™ MS(PEG)4 Methyl-PEG-NHS-Ester Reagent

Pegylate amines (-NH2 groups) on proteins (lysine residues) or assay surfaces using MS(PEG)n, amine-reactive (NHS ester), methyl-capped PEG compounds (4 to 24 EG units).

Content And Storage Store desiccated at -20°C.
Product Type NHS-Ester Reagent
Form Solid
Spacer 4 ethylene glycol units
Solubility Water
Reactive Moiety Active Ester, Succinimidyl Ester, NHS Ester
Label Type Polyethylene Glycol (PEG), Blocking Groups
Chemical Reactivity Amine
Product Line Pierce
12

Thermo Scientific™ Pierce™ Sulfhydryl Addition Kit

Modify protein primary amines to create free sulfhydryl groups for labeling, crosslinking or immobilization techniques; complete kit with SATA reagent and hydroxylamine.

14

MilliporeSigma™ Calbiochem™ Cleland’s Reagent, ULTROL™ Grade

Protective agent for SH groups

Content And Storage 2°C to 8°C
CAS 12-3-3483
Product Type Calbiochem Cleland’s Reagent
Form Solid
Molecular Weight (g/mol) 154.24
Solubility EtOH, Water
Purity ≥99% by titration
Synonym Dithiothreitol, DTT
Molecular Formula C4H10O2S2
15

MilliporeSigma™ Calbiochem™ Cleland’s Reagent, Molecular Biology Grade

Protective agent for SH groups

Content And Storage 2°C to 8°C
CAS 12-3-3483
Product Type Calbiochem Cleland’s Reagent
Form Crystalline Solid
Molecular Weight (g/mol) 154.24
Solubility EtOH, Water
Purity ≥99% by titration
Synonym 1,4-Dithiothreitol, DTT
Molecular Formula C4H10O2S2