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Protein Modification Reagents

Chemical agents used to modify the amino acid side chains of proteins in order to alter their native charges, block or expose reactive binding sites, inactivate functional groups, and change functional groups to create targets for crosslinking and labeling.
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1 – 15 of 120 results
1

Thermo Scientific™ Immobilized Pepsin (Agarose Resin)

Generate and purify Fab and F(ab')2 fragments from antibodies with acidic endopeptidase (pepsin) immobilized onto beaded agarose resin.

2

Thermo Scientific™ Pierce™ Sodium meta-Periodate

Gently oxidize glycoprotein carbohydrate sugars to create reactive aldehydes (carbonyls) for crosslinking and immobilization using NaIO4 (CAS 7790-28-5).

3

Thermo Scientific™ Pierce™ Hydroxylamine-HCl

NH2OH (CAS 7803-49-8) to cleave Asn-Gly peptide bonds or deprotect sulfhydryls following S-acetylthioacetate modification with SATA reagent.

4

Thermo Scientific™ MA(PEG)12 Methyl-PEG-Amine Compound

MA(PEG)n: methyl- and amine-capped polyethylene glycol compounds containing 4 to 24 PEG units; use for surface-modification and molecule-pegylation applications.

Content And Storage Upon receipt store product at -20°C protected from moisture. Product is shipped at ambient temperature.
Product Type Amine Compound
Form Solid
Spacer 12 ethylene glycol units
Solubility Water
Reactive Moiety Amine, Primary Amine
Label Type Polyethylene Glycol (PEG), Blocking Groups
Chemical Reactivity Aldehyde
5

Thermo Scientific™ CA(PEG)8 Carboxy-PEG-Amine Compound

CA(PEG)n: pegylated amino acids of the form carboxy-PEG-amine; with 4 to 24 polyethylene glycol units; for surface- and molecule-pegylation applications.

Content And Storage Store desiccated at 4°C. Shipped at ambient temperature.
Product Type Amine Compound
Spacer 8 ethylene glycol units
Solubility Water
Reactive Moiety Amine, Carboxylic Acid, Primary Amine
Label Type Conjugating Groups, Polyethylene Glycol (PEG)
6

Thermo Scientific™ CA(PEG)24 Carboxy-PEG-Amine Compound

CA(PEG)n: pegylated amino acids of the form carboxy-PEG-amine; with 4 to 24 polyethylene glycol units; for surface- and molecule-pegylation applications.

Content And Storage Store desiccated at 4°C. Shipped at ambient temperature.
Product Type Amine Compound
Spacer 24 ethylene glycol units
Solubility Water
Reactive Moiety Amine, Carboxylic Acid, Primary Amine
Label Type Conjugating Groups, Polyethylene Glycol (PEG)
7

Thermo Scientific™ Pierce™ Sulfo-NHS-Acetate

Amine-reactive (NHS ester) compound to permanently block primary amines (e.g., protein lysine side chains) to prevent interactions or later conjugation.

8

Thermo Scientific™ Pierce™ HRV 3C Protease Solution Kit (2 units/μL)

Remove fusion tags from proteins with the HRV 3C cleavage sequence with this recombinant cysteine protease that is dual tagged for easy removal from the sample after cleavage.

Content And Storage Store at -20°C.
Product Type Protease
Form Kit
Product Line Pierce
9

Invitrogen™ Thiol and Sulfide Quantitation Kit  DFS Item

Ultrasensitive colorimetric assay for quantifying both protein and nonprotein thiols

10

MilliporeSigma™ Novagen™ Overnight Express™ Autoinduction System 2

Used for expression of proteins in multiple cultures.

Content And Storage Multiple storage requirements
11

MilliporeSigma™ Proteinase K Solution, 600mAU/mL

Efficient removal of proteins from nucleic acid solutions

Content And Storage -20°C
Product Type Proteinase K
12

MilliporeSigma™ Aminopeptidase N, Rat

Levels of aminopeptidase N are elevated in cancer subjects and correlate with tumor load, and thus, enzyme is believed to play role in angiogenesis

13

MilliporeSigma™ Calbiochem™ TPEN

Lipid-soluble heavy metal chelator that crosses artificial and natural membranes

14

Thermo Scientific Chemicals Papain, Carica Papaya Latex

CAS: 9001-73-4 Synonym: EC 3.4.22.2

CAS 9001-73-4
Synonym EC 3.4.22.2
15

MilliporeSigma™ Calbiochem™ Sialyl Lewis x, Sodium Salt

Acts as minimal binding lig for E-selectins.

Content And Storage -20°C