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HPLC Columns and Cartridges

Pre-packed columns, cartridges, and guard columns for separation of biomolecules and organic/inorganic analytes; includes normal/reversed phase HPLC, UHPLC, LC-MS, HILIC, mixed-mode, ion exchange, ligand exchange, and affinity column formats.
HPLC Columns (3,954)
HPLC Guard Columns and Cartridges (554)
HPLC Guard Column Accessories (33)

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1 – 15 of 1,268 results
1

Thermo Scientific™ ProPac™ WAX-10 HPLC Columns

For exceptionally high resolution and efficiency when separating protein variants, use ProPac WAX-10 LC Columns.

Pore Size Nonporous
Particle Size 10 μm
Stationary Phase Tertiary Amine
Temperature 60°C
Phase Ion Exchange
Packing Material Spherical, Nonporous Polymer
Column Type Ion Exchange
pH 2 to 12
Product Line ProPac
2

Thermo Scientific™ Hypersil GOLD™ Silica HPLC Columns

Efficiently separate nonpolar and moderately polar organic compounds by normal phase chromatography using Thermo Scientific™ Hypersil GOLD™ Silica LC Columns.

Pore Size 175 Å
Stationary Phase Silica
Temperature 60°C
Phase Normal Phase
Column Type Normal Phase
pH 2 to 8
Surface Area 220 m²/g
USP Type L3
3

Thermo Scientific™ HyPURITY™ C18 HPLC Columns, 3μm Particle Size

Thermo ScientificTM HyPURITYTM C18 HPLC Columns are available in limited dimensions. Please contact Customer Service for more details.

4

Cytiva HiScale™ Columns Packed with Superdex™ Increase or Superose™ Increase Resins

Similar to the new-generation Superdex™ Increase and Superose™ Increase Size Exclusion Chromatography (SEC) Columns, but for use with purifying larger volumes of up to 8.5 mL

Type Column
Content And Storage Store at 4°C to 30°C, 20% Ethanol
For Use With Size Exclusion Chromatography (SEC)
Quantity 1 Ea.
Max. Pressure 2 MPa
5

Thermo Scientific™ Acclaim™ Mixed Mode HILIC-1 HPLC Columns

Get all the advantages of reversed-phase and hydrophilic interaction liquid chromatography (HILIC) in one column with the Thermo Scientific™ Acclaim™ Mixed-Mode HILIC-1 column.

Pore Size 120 Å
Stationary Phase Hydrophobic Alkyl Chain with a Diol Group
Temperature 50°C
Phase Reversed Phase and HILIC
Endcapped Proprietary
Column Type Mixed Mode
pH 2.5 to 7.5
Surface Area 300 m²/g
Product Line Acclaim
USP Type N/A
6

Thermo Scientific™ Acclaim™ Surfactant HPLC Columns

Use for outstanding separation of anionic, nonionic, and cationic surfactants with ELSD and RI detectors.

Pore Size 120 Å
Carbon Load 12%
Stationary Phase Proprietary
Temperature 60°C
Endcapped Yes
Column Type Specialty/Application Specific
pH 2.5 to 7.5
Surface Area 300 m²/g
Product Line Acclaim
7

Thermo Scientific™ Acclaim™ HILIC-10 HPLC Columns

Use this HILIC column to retain and separate highly polar molecules that are unretained by reversed-phase chromatography.

Pore Size 120 Å
Carbon Load 8%
Stationary Phase Proprietary
Temperature 70°C
Phase HILIC
For Use With LC/MS
Endcapped Yes
Column Type HILIC
pH 2 to 8
Surface Area 300 m²/g
Product Line Acclaim
8

Thermo Scientific™ Accucore™ aQ C18 Polar Endcapped HPLC Columns

Use this column, with its specially designed solid core, for the separation of compounds in highly aqueous mobile phases.

Pore Size 80 Å
Stationary Phase C18
Temperature 70°C
Phase Reversed Phase
Endcapped Polar
Column Type Reversed Phase
Surface Area 130 m²/g
Max. Pressure 14500 psi (1000 bar)
Particle Size 2.6 μm
Carbon Load 9%
Packing Material Spherical, Solid Core, Ultrapure Silica
pH 2 to 9
Particle Shape Spherical Solid Core
Product Line Accucore
USP Type L1
9

Thermo Scientific™ Accucore™ PFP HPLC Columns

Use these solid core particle columns to analyze difficult-to-resolve mixtures including DOA and pharmaceuticals.

Pore Size 80 Å
Stationary Phase PFP (Pentafluorophenylpropyl)
Temperature 70°C
Phase Reversed Phase
Endcapped Yes
Column Type Reversed Phase
Surface Area 130 m²/g
Max. Pressure 14500 psi (1000 bar)
Particle Size 2.6 μm
Carbon Load 5%
Packing Material Spherical, Solid Core, Ultrapure Silica
pH 2 to 8
Product Line Accucore
USP Type L43
10

Thermo Scientific™ Accucore™ C18 HPLC Columns

Use this column, with its specially designed solid core, for a broad range of nonpolar analytes across multiple applications.

Pore Size 80 Å
Particle Size 2.6 μm
Carbon Load 9%
Stationary Phase C18
Temperature 70°C
Phase Reversed Phase
Endcapped Yes
Column Type Reversed Phase
pH 1 to 11
Surface Area 130 m²/g
Particle Shape Spherical Solid Core
USP Type L1
11

Thermo Scientific™ Accucore™ HILIC HPLC Columns

Offer enhanced retention of polar and hydrophilic analytes with Thermo Scientific™ Accucore™ HILIC LC Columns.

Pore Size 80 Å
Particle Size 2.6 μm
Stationary Phase Silica
Temperature 70°C
Phase Normal Phase and HILIC
Packing Material Spherical, Solid Core, Ultrapure Silica
Column Type Mixed Mode
pH 2 to 8
Surface Area 130 m²/g
Particle Shape Spherical Solid Core
Max. Pressure 14500 psi (1000 bar)
Product Line Accucore
USP Type L3
12

Thermo Scientific™ Accucore™ RP-MS HPLC Columns

Obtain an excellent combination of speed and quality of separation using these solid core columns that are optimized for LC-MS and UHPLC-MS methods.

Pore Size 80 Å
Particle Size 2.6 μm
Carbon Load 7%
Phase Reversed Phase
Endcapped Yes
Column Type Reversed Phase
pH 2 to 9
Surface Area 130 m²/g
Particle Shape Spherical Solid Core
13

Thermo Scientific™ Accucore™ Phenyl-Hexyl HPLC Columns

Use this solid core column for fast, high-resolution separations of aromatic and moderately polar compounds.

Pore Size 80 Å
Temperature 70°C
Phase Reversed Phase
Endcapped Yes
Column Type Reversed Phase
Surface Area 130 m²/g
Max. Pressure 14500 psi (1000 bar)
Particle Size 2.6 μm
Carbon Load 5%
Packing Material Spherical, Solid Core, Ultrapure Silica
pH 2 to 8
Particle Shape Spherical Solid Core
Product Line Accucore
USP Type L11
14

Thermo Scientific™ POROS™ R2 Prepacked Reversed-Phase Columns

Thermo Scientific™ POROS™ Prepacked Reversed-Phase Column. POROS R2 is a 2000 angstrom pore size Poly[styrenevinylbenzene] particle, suitable for the reversed-phase separation of biomolecules.

Shipping Condition Room Temperature
Pore Size 2000 Å
Content And Storage Store at room temperature.
Stationary Phase Phenyl
Binding Capacity 10 mg/mL (Lysozyme, 1% acetonitrile)
Column Type Reversed Phase
Quantity 1 Column
Product Line POROS
15

Thermo Scientific™ OLIGO™ R3 Reversed Phase Columns

Thermo Scientific™ Oligo™ R3 bulk resin is a rigid polymeric bead designed for reversed-phase chromatography of polynucleotides and other biomolecules.

Shipping Condition Room Temperature
Pore Size 350 Å
Content And Storage Store at room temperature.
Stationary Phase Phenyl
Length (Metric) 100 mm
Column Type Reversed Phase
Volume (Metric) 1.7 mL
Dimensions 4.6 x 100 mm
Quantity 1 Column
Max. Pressure 2400 psi (170 bar)
Column Format Prepacked Column
Particle Size 30 μm
Type Analytical Column
Diameter (Metric) 4.6 mm
Product Line POROS