Protease Inhibitors and Phosphatase Inhibitors
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Thermo Scientific™ Protease Inhibitor Cocktails
Protect your sample from proteolytic degradation during cell lysis with these broad-spectrum protease inhibitor cocktails.
| Composition | Proprietary formulation |
|---|---|
| Form | Liquid |
| Formulation | Proprietary components in DMSO |
MilliporeSigma™ Calbiochem™ Calpain Inhibitor VI
The Calpain Inhibitor VI, also referenced under CAS 190274-53-4, controls the biological activity of Calpain. This small molecule/inhibitor is primarily used for Protease Inhibitors applications.
| Content And Storage | Protect from light |
|---|---|
| CAS | 190274-53-4 |
| Form | Lyophilized |
| Target Proteins | μ-calpain |
| Solubility | DMSO |
| Color | White |
| Purity | 97% by HPLC |
| Molecular Formula | C17H25FN2O4S |
| Formula Weight | 372.5g/mol |
MilliporeSigma™ Calbiochem™ JAK Inhibitor I
JAK Inhibitor I, CAS 457081-03-7, is a potent, reversible, cell-permeable, and ATP-competitive inhibitor of JAK 1 (IC50 = 15 nM), JAK2 (IC50 = 1 nM), JAK3 (Ki = 5 nM) and Tyk2 (IC50 = 1 nM).
| Content And Storage | Protect from light |
|---|---|
| CAS | 457081-03-7 |
| Form | Solid |
| Target Proteins | murine JAK1 |
| Solubility | DMSO |
| Color | Off-white |
| Purity | 98% by HPLC |
| Molecular Formula | C18H16FN3O |
| Formula Weight | 309.3g/mol |
MilliporeSigma™ Calbiochem™ JNK Inhibitor II
JNK Inhibitor II. SP600125, CAS 129-56-6, is a potent, cell-permeable, selective, and ATP competitive inhibitor of c-Jun N-terminal kinase (JNK; IC50 = 40 nM for JNK-1 & JNK-2 & 90 nM for JNK-3).
| Content And Storage | Protect from light |
|---|---|
| CAS | 129-56-6 |
| Form | Solid |
| Target Proteins | JNK 1, JNK 2, JNK 3 |
| Solubility | DMSO |
| Color | Yellowish Orange |
| Purity | 98% by HPLC |
| Molecular Formula | C14H8N2O |
| Formula Weight | 220.2g/mol |
MilliporeSigma™ Calbiochem™ Rho Kinase Inhibitor
The Rho kinase inhibitor, CAS 872543-07-6, is a cell-permeable, highly specific, reversible, potent, and ATP-competitive inhibitor of Rho-associated kinase (ROCK; Ki = 1.6 nM).
| Content And Storage | Hygroscopic, Protect from light |
|---|---|
| Form | Solid |
| Target Proteins | ROCK |
| Solubility | H2O or MeOH |
| Color | White |
| Purity | 95% by HPLC |
| Molecular Formula | C16H21N3O2S·2HCl |
| Formula Weight | 392.3g/mol |
Thermo Scientific™ Halt™ Protease Inhibitor Cocktail (100X)
Inhibit proteolytic degradation during cell lysis and protein extraction with these ready-to-use concentrated stock solutions of protease inhibitors.
| Buffer | Lysis Buffer |
|---|---|
| Content And Storage | Upon receipt store at 4°C |
| Inhibitors | Protease Inhibitor |
| Form | Liquid |
| Product Type | Protease Inhibitor Cocktail |
| Reagent Type | Protease Inhibitor |
| Product Line | Halt |
Thermo Scientific™ Pierce™ Phosphatase Inhibitor Mini Tablets
Thermo Scientific™ Pierce Phosphatase Inhibitor Mini Tablets provide complete cell lysate and biological sample protection from dephosphorylation with a broad spectrum phosphatase inhibitor formulation.
MilliporeSigma™ Calbiochem™ E-64 Protease Inhibitor
The E-64 Protease Inhibitor, also referenced under CAS 66701-25-5, controls the biological activity of E-64 Protease. This small molecule/inhibitor is primarily used for Protease Inhibitors applications.
| CAS | 66701-25-5 |
|---|---|
| Form | Solid |
| Target Proteins | cysteine proteases |
| Solubility | DMSO |
| Color | White |
| Purity | 98% by HPLC |
| Molecular Formula | C15H27N5O5 |
| Formula Weight | 357.4g/mol |
MilliporeSigma™ Calbiochem™ Cathepsin G Inhibitor I
The Cathepsin G Inhibitor I, also referenced under CAS 429676-93-7, controls the biological activity of Cathepsin G. This small molecule/inhibitor is primarily used for Protease Inhibitors applications.
| Content And Storage | Protect from light |
|---|---|
| CAS | 429676-93-7 |
| Form | Solid |
| Target Proteins | cathepsin G |
| Solubility | DMSO |
| Color | White |
| Purity | 98% by HPLC |
| Molecular Formula | C36H33N2O6P |
| Formula Weight | 620.6g/mol |
MilliporeSigma™ Calbiochem™ Autophagy Inhibitor, 3-MA
Autophagy Inhibitor, 3-MA, CAS 5142-23-4, is a cell-permeable autophagic sequestration blocker. Acts as an inhibitor of III PI3-Kinase.
| Content And Storage | Protect from light |
|---|---|
| CAS | 5142-23-4 |
| Form | Powder |
| Solubility | DMSO or H2O |
| Color | White to Faint Yellow |
| Purity | 95% by HPLC |
| Molecular Formula | C6H7N5 |
| Formula Weight | 149.2g/mol |
MilliporeSigma™ Calbiochem™ AMPK Inhibitor, Compound C
AMPK Inhibitor, Compound C, CAS 866405-64-3, is a cell-permeable compound that inhibits KDR/VEGFR2, ALK2/BMPR-I, and AMPK kinase activities (IC50 = 25.1, 148, and 234.6 nM, respectively).
| Content And Storage | Protect from light |
|---|---|
| CAS | 866405-64-3 |
| Form | Solid |
| Target Proteins | AMPK |
| Solubility | DMSO, 100 mM HCl, or MeOH |
| Color | Light Yellow |
| Purity | 95% by HPLC |
| Molecular Formula | C24H25N5O |
| Formula Weight | 399.5g/mol |
MilliporeSigma™ Calbiochem™ Akt Inhibitor V, Triciribine
The Akt Inhibitor V, Triciribine, also referenced under CAS 35943-35-2, controls the biological activity of Akt.
| Content And Storage | Protect from light |
|---|---|
| CAS | 35943-35-2 |
| Form | Solid |
| Target Proteins | Akt1, Akt 2, Akt3 |
| Solubility | DMSO |
| Purity | 95% by HPLC |
| Molecular Formula | C13H16N6O4 |
| Formula Weight | 320.3g/mol |
MilliporeSigma™ Calbiochem™ γ-Secretase Inhibitor XX
This γ-secretase inhibitor, CAS 209984-56-5, is a cell-permeable dibenzazepine compound that lowers both brain and plasma Aβ40 levels by ≈72% in Tg2576 mutant APP transgenic mouse model.
| Content And Storage | Protect from light |
|---|---|
| CAS | 209984-56-5 |
| Form | Solid |
| Target Proteins | γ-secretase |
| Solubility | DMSO |
| Color | White |
| Purity | 95% by HPLC |
| Molecular Formula | C26H23F2N3O3 |
| Formula Weight | 463.4g/mol |
Thermo Scientific™ Pierce™ Protease Inhibitor Mini Tablets
Thermo Scientific™ Pierce Protease Inhibitor Mini Tablets are broad-spectrum protease inhibitors that are highly effective at preventing proteolytic degradation for cell lysis and protein extraction experiments
| Content And Storage | 2°C to 8°C |
|---|---|
| Format | Tablet |
| Sufficient For | 1 tablet is sufficient for 10 mL |
| Quantity | 2 Tablets |
| For Use With (Application) | protein purification, western blotting |
Thermo Scientific™ Pierce™ Protease Inhibitor Tablets, EDTA-free
Thermo Scientific™ Pierce Protease Inhibitor Tablets are broad-spectrum protease inhibitors that are highly effective at preventing proteolytic degradation for cell lysis and protein extraction experiments