Bioactive Small Molecules

Guanidine Hydrochloride (Colorless-to-White Crystals), Fisher BioReagents™

For isolation of RNA from cell extracts | CAS: 50-01-1 | CH6ClN3

Molecular Probes™ Probenecid, Water Soluble

Probenecid, Water Soluble

Invitrogen™ Muscimol, BODIPY™ TMR-X Conjugate

Muscimol is a powerful agonist of the GABA_A receptor and has been widely used to reversibly inactivate localized groups of neurons.

Invitrogen™ Methotrexate, Fluorescein, triammonium Salt (Fluorescein Methotrexate)

To probe DHFR expression

Invitrogen™ Nigericin, Free Acid

For intracellular calibration of fluorescence response of cytosolic pH indicators

Invitrogen™ Nile Red

For use with fluorescence microscopy

Invitrogen™ Pepstatin A, BODIPY™ FL Conjugate

For the study of cathepsin D trafficking in cells by fluorescence microscopy

Invitrogen™ Octadecyl Rhodamine B Chloride (R18)

Lipophilic octadecyl rhodamine B binds to membranes with fluorophore at aqueous interface and alkyl tail protruding into lipid interior

Invitrogen™ ANTS (8-Aminonaphthalene-1,3,6-Trisulfonic Acid, Disodium Salt)

Polyanionic dye often used in combination with the cationic quencher DPX for membrane fusion or permeability assays, including complement-mediated immune lysis

Invitrogen™ A-23187 Free Acid (Calcimycin)

Commonly used for in situ calibrations of fluorescent Ca²⁺ indicators

Tiamulin fumarate, 95%

Invitrogen™ Fluorescein-5-(and-6)-Sulfonic Acid, Trisodium Salt

Cell impermeant

Invitrogen™ FR-31564 (Fosmidomycin, Sodium Salt)

Blocks a pathway of isoprene synthesis

Invitrogen™ Latrunculin A

For applications involving cell structure

Invitrogen™ Ionomycin, Calcium Salt

Ionomycin is an effective Ca²⁺ ionopohre that is commonly used to both modify intracellular Ca²⁺ concentrations and to calibrate fluorescent Ca²⁺ indicators when studying the regulatory properties of Ca²⁺ in cellular processes.