missing translation for 'onlineSavingsMsg'
Learn More

Phospho-PDPK1 (Ser241) Recombinant Rabbit Monoclonal Antibody (PDK1S241-F7), PE, Invitrogen™

Rabbit Recombinant Monoclonal Antibody

Supplier:  Thermo Fisher Scientific MA537089

 Afficher plus de versions de ce produit

Numéro de catalogue. PIMA537089


Il en reste null
Découvrez plus d'offres spéciales

Description

Description

PDPK1 (3 Phosphoinositide Dependent Protein Kinase 1) phosphorylates AGC kinases. PDPK1 activates conventional PKC and PKC zeta through phosphorylation of critical threonine residues in the activation loop. PDPK1 also phosphorylates Protein Kinase B (PKB) at threonine 308 in the presence of phosphatidylinositol-3,4,5-trisphosphate. Active Akt inactivates Glycogen Synthase Kinase 3 (GSK3), eventually leading to the dephosphorylation and activation of glycogen synthase, and the stimulation of glycogen synthesis. Because of the role that PDPK1 plays in insulin-induced glycogen synthesis and PKC activation, it is a potentially important target for metabolic drug research.
Spécifications
Afficher plus de résultats
missing translation for 'recommendations'

missing translation for 'recommendations'

Videos
FDS
Documents

Documents

Promotions

Promotions