Protein Purification
MilliporeSigma™ Calbiochem™ Fucosyltransferase Inhibitor, 2F-Peracetyl-Fucose
2F-Peracetyl-Fucose is a cell-permeable fluorinated fucose derivative that acts as an inhibitor of fucosyltransferases following its uptake and metabolic transformation into a GDP-fucose mimetic.
MilliporeSigma™ Calbiochem™ β-Glycerophosphate, Disodium Salt, Pentahydrate
A phosphate group donor in matrix mineralization studies that acts as a protein phosphatase inhibitor.
MilliporeSigma™ Calbiochem™ Ro-20-1724
A cell-permeable, selective inhibitor of cAMP-specific phosphodiesterase (PDE IV; IC50 = 2 μM).
MilliporeSigma™ Calbiochem™ InSolution™ γ-Secretase Inhibitor IX
InSolution™ g-Secretase Inhibitor IX, CAS 208255-80-5, is a 25 mM (5 mg/462 μl or 10 mg/924 μl) solution of g-secretase Inhibitor IX (DAPT; Cat. No. 565770) in DMSO.
MilliporeSigma™ Calbiochem™ (-)-Blebbistatin
The active enantiomer of (±)-Blebbistatin that accounts for the inhibitory activity towards ATPase and myosin II-dependent cellular processes.
MilliporeSigma™ Calbiochem™ (±)-Blebbistatin
(±)-Blebbistatin, CAS 674289-55-5, is a cell-permeable, selective, and reversible inhibitor of nonmuscle myosin II. Blocks cell blebbing and disrupts cell migration & cytoKinesis in vertebrate cells.
MilliporeSigma™ Calbiochem™ c-Myc Inhibitor
The c-Myc Inhibitor, also referenced under CAS 403811-55-2, controls the biological activity of c-Myc.
MilliporeSigma™ Calbiochem™ PKA Inhibitor 14-22 Amide, Cell-Permeable, Myristoylated
PKA Inhibitor 14-22 Amide is myristoylated at the N-terminus that enhances its cell-permeability. The non-myristoylated version is shown to be a specific inhibitor of PKA (Ki = 36 nM).
MilliporeSigma™ Calbiochem™ Nocodazole
Inhibitor of mitosis.
MilliporeSigma™ Calbiochem™ Okadaic Acid, Prorocentrum sp.
Okadaic Acid, CAS 78111-17-8, is a highly potent inhibitor of protein phosphatase 1 (IC50 = 10-15 nM) and 2A (IC50 = 0.1 nM).
MilliporeSigma™ Calbiochem™ Triptolide, Tripterygium wilfordii
A novel diterpene triepoxide isolated from the Chinese herb Tripterygium wilfordii that acts as a potent immunosuppressant and anti-inflammatory agent.
MilliporeSigma™ Calbiochem™ InSolution™ PPACK, 2HCl
A 25 mM (5 mg/357 μl) sterile-filtered solution of PPACK, 2HCl in H2O.
MilliporeSigma™ Calbiochem™ SKP2 E3 Ligase Inhibitor I, C1
A cell-permeable rhodanine compound that upregulates cellular p21Cip1/Waf1 and p27Kip1 protein levels (10μM for 16 h in 501 Mel cultures) by preventing Skp2-Cks1-mediated substrate recruitment without affecting the F-box E3 ubiquitin ligase Skp2 interaction with Cks1 or the SCF (Skp1-cullin1-F-box) c
MilliporeSigma™ Calbiochem™ Dicoumarol
A cell-permeable quinone reductase inhibitor with anticoagulant properties.
MilliporeSigma™ Calbiochem™ InSolution™Blebbistatin, Racemic
InSolution™Blebbistatin, Racemic, is a 50mm in 90% DMSO. A cell-permeable, selective, and reversible inhibitor of nonmuscle myosin II. Blocks cell blebbing and disrupts cell migration and cytoKinesis.