Modifying Enzymes

Fisher BioReagents™ Proteinase K (Tritirachium album/Molecular Biology)

Fisher Scientific Edge
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Thermo Scientific™ T4 Polynucleotide Kinase (10 U/μL)

T4 Polynucleotide Kinase (T4 PNK) catalyzes the transfer of the gamma-phosphate from ATP to the 5'-OH group of oligonucleotides, ss and dsDNA and RNA.

Thermo Scientific™ Proteinase K, recombinant, PCR grade

Degrade proteins even in the presence of detergents with Proteinase K, a broad-range endolytic protease widely used for digestion of proteins in nucleic acid preparations.

Invitrogen™ Proteinase K Solution (20 mg/mL), RNA grade  

Proteinase K from the fungus Engyodontium album is a nonspecific serine protease that is useful for general digestion of proteins.

MP Biomedicals™ Hyaluronidase, Bovine Testes

Bovine Testes

MilliporeSigma™ Calbiochem™ FragEL™ TdT Enzyme DNA Fragmentation Detection Kit, Colorimetric

For detection of apoptosis at individual cell level

Thermo Scientific Chemicals Pectinase, Aspergillus niger

Used in plant protoplast preparation to digest cell wall prior to organelle isolation. Pectinase helps facilitate the maceration of plant materials and extraction processes including organelle preparation.

Applied Biosystems™ Exonuclease I, high concentration, (20 units/μL)  

Exonuclease I can be used to measure the endonucleolytic cleavage of covalently closed circular single-stranded DNA reacted with an endonuclease of interest.

Thermo Scientific Chemicals Ascorbate oxidase, from Cucurbita sp.

MilliporeSigma™ Upstate p300, HAT Domain Recombinant Enzyme

Recombinant GST-fusion protein corresponding to amino acids 1066-1707 of human p300.

Invitrogen™ CIAP (Calf Intestinal Alkaline Phosphatase), 20 U/μL  

Phosphomonoesterase that removes 3' and 5' phosphates from DNA and RNA

Thermo Scientific™ DNase I, RNase-free (supplied with MnCl2) (1 U/μL)

Endonuclease that nonspecifically cleaves single- and double-stranded DNA to release di-, tri-, and oligonucleotides with 5'-phosphate and 3'-OH groups.

Thermo Scientific™ RNase A/T1 Mix

Get the RNA degradation activity of both RNase A and RNase T1 with Thermo Scientific™ RNase A/T1 Mix.

Thermo Scientific™ Lambda Exonuclease (10 U/μL)

Lambda Exonuclease is a highly processive exodeoxyribonuclease that selectively digests the 5'-phosphorylated strand of double-stranded DNA in 5'-3' direction.

Thermo Scientific™ Klenow Fragment (10 U/μL)

Klenow Fragment is the Large Fragment of DNA Polymerase exhibiting 5'→3' polymerase, 3'→5' exonuclease (proofreading) activities, but lacking 5'→3' exonuclease activity.