Signal Transduction Reagents and Kits
Thermo Scientific Chemicals Colcemid, 98+%
CAS: 477-30-5 Molecular Formula: C21H25NO5,C21H25NO5 Synonym: Demecolcine; N-Methyl-N-desacetylcolchicine
Thermo Scientific Chemicals Ingenol 3-angelate, 98%
CAS: 75567-37-2 Molecular Formula: C25H34O6,C25H34O6 Molecular Weight (g/mol): 430.54 InChI Key: VDJHFHXMUKFKET-WDUFCVPESA-N IUPAC Name: (1S,4S,5S,6R,9S,10R,12R,14R)-5,6-dihydroxy-7-(hydroxymethyl)-3,11,11,14-tetramethyl-15-oxotetracyclo[7.5.1.0¹,⁵.0¹⁰,¹²]pentadeca-2,7-dien-4-yl (2Z)-2-methylbut-2-enoate SMILES: C\C=C(\C)C(=O)O[C@H]1C(C)=C[C@@]23[C@H](C)C[C@@H]4[C@H]([C@H](C=C(CO)[C@@H](O)[C@]12O)C3=O)C4(C)C
Thermo Scientific Chemicals Cathepsin G Inhibitor I
CAS: 429676-93-7 Molecular Formula: C36H33N2O6P
Thermo Scientific Chemicals LY 294002, 98%
CAS: 154447-36-6 Molecular Formula: C19H17NO3 Synonym: 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one;
Thermo Scientific Chemicals Aurora Kinase/Cdk Inhibitor
CAS: 443797-96-4 Molecular Formula: C15H12F2N6O3S,C15H12F2N6O3S Molecular Weight (g/mol): 394.36 InChI Key: KDKUVYLMPJIGKA-UHFFFAOYSA-N Synonym: 4-(5-Amino-1-(2,6-difluorobenzoyl)-1H-[1,2,4]triazol-3-ylamino)-benzenesulfonamide; IUPAC Name: 4-{[5-amino-1-(2,6-difluorobenzoyl)-1H-1,2,4-triazol-3-yl]amino}benzene-1-sulfonamide SMILES: NC1=NC(NC2=CC=C(C=C2)S(N)(=O)=O)=NN1C(=O)C1=C(F)C=CC=C1F
Thermo Scientific Chemicals gamma-Secretase Inhibitor I
CAS: 133407-83-7 Molecular Formula: C26H41N3O5,C26H41N3O5 Molecular Weight (g/mol): 475.63 InChI Key: RNPDUXVFGTULLP-UHFFFAOYNA-N Synonym: Z-Leu-Leu-Nle-CHO (Nle = Norleucine); IUPAC Name: benzyl N-[3-methyl-1-({3-methyl-1-[(1-oxohexan-2-yl)carbamoyl]butyl}carbamoyl)butyl]carbamate SMILES: CCCCC(NC(=O)C(CC(C)C)NC(=O)C(CC(C)C)NC(=O)OCC1=CC=CC=C1)C=O
Thermo Scientific Chemicals IGF-1R Inhibitor, PPP
CAS: 477-47-4 Molecular Formula: C22H22O8,C22H22O8 Molecular Weight (g/mol): 414.41 InChI Key: YJGVMLPVUAXIQN-HAEOHBJNSA-N Synonym: Insulin-like Growth Factor-1 Receptor Inhibitor; Picropodophyllin IUPAC Name: (10R,11S,15R,16R)-16-hydroxy-10-(3,4,5-trimethoxyphenyl)-4,6,13-trioxatetracyclo[7.7.0.0³,⁷.0¹¹,¹⁵]hexadeca-1,3(7),8-trien-12-one SMILES: COC1=CC(=CC(OC)=C1OC)[C@H]1[C@H]2[C@H](COC2=O)[C@@H](O)C2=CC3=C(OCO3)C=C12
Thermo Scientific Chemicals GSK-3beta Inhibitor VIII
CAS: 487021-52-3 Molecular Formula: C12H12N4O4S,C12H12N4O4S Molecular Weight (g/mol): 308.31 InChI Key: YAEMHJKFIIIULI-UHFFFAOYSA-N Synonym: AR-A014418 IUPAC Name: 1-[(4-methoxyphenyl)methyl]-3-(5-nitro-1,3-thiazol-2-yl)urea SMILES: COC1=CC=C(CNC(=O)NC2=NC=C(S2)[N+]([O-])=O)C=C1
Thermo Scientific Chemicals Calpain Inhibitor I, 95+%
CAS: 110044-82-1 Molecular Formula: C20H37N3O4,C20H37N3O4 Molecular Weight (g/mol): 383.53 InChI Key: FMYKJLXRRQTBOR-BZSNNMDCSA-N Synonym: Ac-LLnL-CHO; ALLN IUPAC Name: (2S)-2-[(2S)-2-acetamido-4-methylpentanamido]-4-methyl-N-[(2S)-1-oxohexan-2-yl]pentanamide SMILES: CCCC[C@H](NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CC(C)C)NC(C)=O)C=O
Thermo Scientific Chemicals PTP1B Inhibitor
CAS: 765317-72-4 Molecular Formula: C26H19Br2N3O7S3,C26H19Br2N3O7S3 Molecular Weight (g/mol): 741.44 InChI Key: SXKBTDJJEQQEGE-UHFFFAOYSA-N Synonym: 3-(3,5-Dibromo-4-hydroxybenzoyl)-2-ethyl-N-[4-(2-thiazolylsulfamoyl)phenyl]benzofuran-6-sulfonamide IUPAC Name: 3-(3,5-dibromo-4-hydroxybenzoyl)-2-ethyl-N-{4-[(1,3-thiazol-2-yl)sulfamoyl]phenyl}-1-benzofuran-6-sulfonamide SMILES: CCC1=C(C(=O)C2=CC(Br)=C(O)C(Br)=C2)C2=CC=C(C=C2O1)S(=O)(=O)NC1=CC=C(C=C1)S(=O)(=O)NC1=NC=CS1
Thermo Scientific Chemicals Sphingosine-1-phosphate
CAS: 26993-30-6 Molecular Formula: C18H38NO5P,C18H38NO5P Synonym: D-erythro-Sphingosine 1-phosphate; S1P
Thermo Scientific Chemicals Z-Val-Val-Nle Diazomethyl Ketone
CAS: 155026-49-6 Molecular Formula: C25H37N5O5,C25H37N5O5 Molecular Weight (g/mol): 487.60 InChI Key: IIPZPLSBQVJCBO-UHFFFAOYNA-N Synonym: C-3890; Z-Val-Val-Nle-DMK IUPAC Name: benzyl N-[1-({1-[(1-diazo-2-oxoheptan-3-yl)carbamoyl]-2-methylpropyl}carbamoyl)-2-methylpropyl]carbamate SMILES: CCCCC(NC(=O)C(NC(=O)C(NC(=O)OCC1=CC=CC=C1)C(C)C)C(C)C)C(=O)C=[N+]=[N-]
Thermo Scientific Chemicals Tioconazole, 98+%
CAS: 65899-73-2 Molecular Formula: C16H13Cl3N2OS Synonym: Thioconazole
Thermo Scientific Chemicals Calpain Inhibitor III, 95+%
CAS: 88191-84-8 Molecular Formula: C22H26N2O4,C22H26N2O4 Molecular Weight (g/mol): 382.46 InChI Key: NGBKFLTYGSREKK-PMACEKPBSA-N Synonym: MDL; Z-Val-Phe-CHO IUPAC Name: benzyl N-[(1S)-2-methyl-1-{[(2S)-1-oxo-3-phenylpropan-2-yl]carbamoyl}propyl]carbamate SMILES: CC(C)[C@H](NC(=O)OCC1=CC=CC=C1)C(=O)N[C@@H](CC1=CC=CC=C1)C=O
Thermo Scientific Chemicals p21-Activated Kinase Inhibitor III, IPA-3
CAS: 42521-82-4 Molecular Formula: C20H14O2S2,C20H14O2S2 Synonym: PAK Inhibitor III; 1,1′-Disulfanediylbis(naphthalen-2-ol)