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Thermo Scientific Chemicals GW-405833
CAS: 180002-83-9 | C23H24Cl2N2O3, C23H24Cl2N2O3 | 447.36 g/mol
Supplier: Thermo Scientific Chemicals J67425MA
Description
It is a potent and selective CB2 receptor partial agonist (EC50 = 0.65 nM; maximum inhibition = 44.6%). Binds with high affinity to both human and rat CB2 receptors and displays ∼ 1200-fold selectivity over CB1 (Ki values are 3.92 and 4772 nM for human recombinant CB2 and CB1 receptors respectively). Produces potent antihyperalgesic effects in several rodent models of pain.
This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.
Spécifications
| 10 mg | |
| -30°C to -10°C | |
| C23H24Cl2N2O3 | |
| L-768242; 1-(2,3-Dichlorobenzoyl)-5-methoxy-2-methyl-3-[2-(4-morpholinyl)ethyl]indole | |
| Soluble in DMSO at 10-15mg/ml. Also soluble in ethanol at ∽5mg/ml. | |
| Solid | |
| COC1=CC=C2N(C(=O)C3=C(Cl)C(Cl)=CC=C3)C(C)=C(CCN3CCOCC3)C2=C1 | |
| 447.36 |
| Off-white | |
| 180002-83-9 | |
| 447.36 | |
| 47°C to 49°C | |
| GW-405833 | |
| FSFZRNZSZYDVLI-UHFFFAOYSA-N | |
| 1-(2,3-dichlorobenzoyl)-5-methoxy-2-methyl-3-[2-(morpholin-4-yl)ethyl]-1H-indole |
Identifiants chimiques
| 180002-83-9 | |
| 447.36 | |
| L-768242; 1-(2,3-Dichlorobenzoyl)-5-methoxy-2-methyl-3-[2-(4-morpholinyl)ethyl]indole | |
| COC1=CC=C2N(C(=O)C3=C(Cl)C(Cl)=CC=C3)C(C)=C(CCN3CCOCC3)C2=C1 |
| C23H24Cl2N2O3 | |
| FSFZRNZSZYDVLI-UHFFFAOYSA-N | |
| 1-(2,3-dichlorobenzoyl)-5-methoxy-2-methyl-3-[2-(morpholin-4-yl)ethyl]-1H-indole |
Sécurité et manipulation
Recommended Storage : Store at -20°C
RUO – Research Use Only