RNA interference (RNAi) is a biological process in which RNA molecules inhibit gene expression or translation by neutralizing targeted mRNA molecules. RNAi controls can be used to accurately interpret the results of experiments involving the RNAi pathway.
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Silencer Select Negative Control No. 1 is a bioinformatically designed, non-targeting siRNA crucial for siRNA experiments. Matching Silencer Select chemistry, it ensures minimal off-target effects and is an essential siRNA negative control for achieving clear, accurate gene silencing results.
The siRNA (annealed) is shipped at ambient temperature as dried down oligonucleotides in a single tube, along with 1.75 ml Nuclease-free Water for resuspension. Store at or below –20°C.
miRNA mimics are small, chemically modified double-stranded RNA molecules designed to specifically bind to and mimic endogenous miRNA molecules and enable miRNA functional analysis by up-regulation of miRNA activity.
Silencer Negative Control No. 1 siRNA is a bioinformatically designed, non-targeting siRNA crucial for siRNA experiments. Matching Silencer chemistry, it is an essential negative control siRNA for achieving clear, accurate gene silencing results.