RNAi and RNA Reagents
Invitrogen™ Silencer™ Human Apoptosis siRNA Library
The Silencer™ Human Apoptosis siRNA Library provides investigators with a focused siRNA screening platform targeting apoptosis genes and enabling a detailed analysis of the apoptotic signaling pathway.
Invitrogen™ Silencer™ Select Human Tumor Suppressor siRNA Library
Mutations that cause a loss or reduction in gene function can result in the progression to cancer, usually in combination with other genetic changes. Tumor suppressor genes, or anti-oncogenes, can protect cells on the path to becoming cancerous.
Invitrogen™ Silencer™ Human DNA Damage Response siRNA Library
DNA surveillance proteins monitor DNA integrity, and they can activate cell cycle checkpoints and DNA repair pathways in response to DNA damage. This can prevent potentially deleterious mutations.
Invitrogen™ Silencer™ Human Drug Targets siRNA Library
The Silencer™ Human Drug Targets siRNA Library includes genes involved in apoptosis, senescence, nucleic acid binding, autophagy, DNA repair, and along with characterized nuclear receptors and other genes that are considered potential targets for therapeutics.
Invitrogen™ Silencer™ Human Tumor Suppressor siRNA Library
Mutations that cause a loss or reduction in gene function can result in the progression to cancer, usually in combination with other genetic changes. Tumor suppressor genes, or anti-oncogenes, can protect cells on the path to becoming cancerous.
Invitrogen™ LentiArray™ Human Druggable CRISPR Library
The award-winning Invitrogen™ LentiArray™ Human Druggable Genome Library targets 10,132 genes with up to 4 gRNA per gene target (pooled in a single well) for a total of 40,512 gRNAs.
Invitrogen™ LentiArray™ CRISPR Negative Control Lentivirus, human, non-targeting, with GFP
Negative control gRNAs are essential in screening applications for setting thresholds for hit determination.
Invitrogen™ LentiArray™ CRISPR Positive Control Lentivirus, human HPRT, with GFP
Optimizing delivery conditions is a critical step in any experiment utilizing the CRISPR/Cas9 system.
Invitrogen™ TrueGuide™ gRNA
Ready-to-use, synthetic gRNAs maximize and simplify the performance of CRISPR-Cas9 genome editing experiments.
Invitrogen™ TrueGuide™ sgRNA Positive Control, CDK4 (human)
Used for the optimization of transfection and verification of editing efficiency in transfected cells.
Invitrogen™ TrueGuide™ sgRNA Positive Control, Rosa26 (mouse)
Used for the optimization of transfection and verification of editing efficiency in transfected cells.
Invitrogen™ LentiArray™ Human Kinase CRISPR Library
The Invitrogen™ LentiArray™ Human Kinase CRISPR Library targets 822 genes with up to 4 gRNA per gene target (pooled in a single well) for a total of 3,288 gRNAs. Libraries are delivered as 100 μL of ready to use lentiviral particles per gene target.