Bioactive Small Molecules

Guanidine Hydrochloride (Colorless-to-White Crystals), Fisher BioReagents™

For isolation of RNA from cell extracts | CAS: 50-01-1 | CH6ClN3

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Invitrogen™ eBioscience™ Monensin Solution (1000X)

Addition of Monensin during the last hours of in vitro activation of cells results in enhanced detection of intracellular cytokines.

Invitrogen™ eBioscience™ Brefeldin A Solution (1000X)

Addition of Brefeldin A during the last hours of in vitro activation of cells results in enhanced detection of intracellular cytokines.

Thermo Scientific™ A-1210477, 95%

Carfilzomib, Thermo Scientific™

CAS: 868540-17-4 Molecular Formula: C40 H57 N5 O7 Molecular Weight (g/mol): 719.92 MDL Number: MFCD11040997 InChI Key: BLMPQMFVWMYDKT-UHFFFAOYNA-N IUPAC Name: 4-methyl-N-(1-{[4-methyl-1-(2-methyloxiran-2-yl)-1-oxopentan-2-yl]carbamoyl}-2-phenylethyl)-2-{2-[2-(morpholin-4-yl)acetamido]-4-phenylbutanamido}pentanamide SMILES: CC(C)CC(NC(=O)C(CCC1=CC=CC=C1)NC(=O)CN1CCOCC1)C(=O)NC(CC1=CC=CC=C1)C(=O)NC(CC(C)C)C(=O)C1(C)CO1

Thermo Scientific Chemicals Ropinirole hydrochloride

CAS: 91374-20-8 Molecular Formula: C16H25ClN2O

Invitrogen™ Bis-ANS (4,4'-Dianilino-1,1'-Binaphthyl-5,5'-Disulfonic Acid, Dipotassium Salt)  

Binds with affinity that is often orders-of-magnitude higher than 1-8-ANS as probe for nonpolar cavities in proteins

Thermo Scientific Chemicals Zoledronic acid monohydrate

CAS: 165800-06-6 Molecular Formula: C5H12N2O8P2

Thermo Scientific Chemicals Gemifloxacin mesylate

CAS: 210353-53-0 Molecular Formula: C19H24FN5O7S

Amentoflavone, Thermo Scientific™

CAS: 1617-53-4 Molecular Formula: C30 H18 O10 Molecular Weight (g/mol): 538.46 InChI Key: YUSWMAULDXZHPY-UHFFFAOYSA-N IUPAC Name: 8-[5-(5,7-dihydroxy-4-oxo-4H-chromen-2-yl)-2-hydroxyphenyl]-5,7-dihydroxy-2-(4-hydroxyphenyl)-4H-chromen-4-one SMILES: OC1=CC=C(C=C1)C1=CC(=O)C2=C(O)C=C(O)C(=C2O1)C1=CC(=CC=C1O)C1=CC(=O)C2=C(O)C=C(O)C=C2O1

Thermo Scientific Chemicals Melanin, synthetic

CAS: 8049-97-6 Molecular Formula: C₁₈H₁₀N₂O₄

Thermo Scientific Chemicals Tenofovir

CAS: 147127-20-6 Molecular Formula: C9 H14 N5 O4 P

Thermo Scientific Chemicals Rutaecarpine

CAS: 84-26-4 Molecular Formula: C18H13N3O

Thermo Scientific Chemicals (+)-trans-Taxifolin

CAS: 480-18-2 Molecular Formula: C₁₅H₁₂O₇

Invitrogen™ Brefeldin A (from Penicillium brefeldianum)  

The fungal metabolite brefeldin A (BFA) has multiple targets in cells and has proven valuable for dissecting the cellular processes, including vesicle formation and kinesin distribution, involved in exporting newly synthesized proteins.