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CHAPS, 98%, Thermo Scientific™

CHAPS, 3-[(3-cholamidopropyl)dimethylammonio]-1-propanesulfonate, CAS # 75621-03-3, is a non-denaturing zwitterionic detergent that can be used for solubilizing membrane proteins.

Manufacturer:  Thermo Fisher Scientific AC436550050

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Catalog No. AC436550050



Description

Description

This Thermo Scientific brand product was originally part of the Acros Organics product portfolio. Some documentation and label information may refer to the legacy brand. The original Acros Organics product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific.

General Description

  • CHAPS (3-((3-cholamidopropyl) dimethylammonio)-1-propanesulfonate) is a zwitterionic non-denaturing detergent
  • It is suitable for applications which require protection of native protein conformation

Applications

  • CHAPS can be used for the solubilization and purification of membrane proteins
  • It is also used in conjunction with nonionic detergents like Triton X-100
  • It can be used as a non-denaturing zwitterionic detergent for the study of membrane chemistry
Specifications

Specifications

CHAPS
White
4.46 to 4.65 % N
Authentic
MFCD00012116
15,2043
5g
UMCMPZBLKLEWAF-GBSSQDIOSA-N
3-[dimethyl-[3-[[(4R)-4-[(3R,5S,7R,8R,9R,10S,12S,13R,14R,17S)-3,7,12-trihydroxy-10,13-dimethyl-2,3,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl]pentanoyl]amino]propyl]azaniumyl]propane-1-sulfonate
134129639
Crystalline Powder
2% Max. (K.F.)
75621-03-3
267.2°C to 271.4°C
98%
C32H58N2O7S
Glass bottle
3-[(3-Cholamidopropyl)dimethylammonio]-1-propanesulfonate
Solubility in water: soluble. Other solubilities: soluble in alcohols like methanol and ethanol
CC(CCC(=O)NCCC[N+](C)(C)CCCS(=O)(=O)[O-])C1CCC2C1(C(CC3C2C(CC4C3(CCC(C4)O)C)O)O)C
614.9
614.9
98%

Chemical Identifiers

75621-03-3
614.9
UMCMPZBLKLEWAF-GBSSQDIOSA-N
134129639
CC(CCC(=O)NCCC[N+](C)(C)CCCS(=O)(=O)[O-])C1CCC2C1(C(CC3C2C(CC4C3(CCC(C4)O)C)O)O)C
C32H58N2O7S
MFCD00012116
3-[(3-Cholamidopropyl)dimethylammonio]-1-propanesulfonate
3-[dimethyl-[3-[[(4R)-4-[(3R,5S,7R,8R,9R,10S,12S,13R,14R,17S)-3,7,12-trihydroxy-10,13-dimethyl-2,3,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl]pentanoyl]amino]propyl]azaniumyl]propane-1-sulfonate
Safety and Handling

Safety and Handling

GHS H Statement
Causes skin irritation.
Causes serious eye irritation.
May cause respiratory irritation.

GHS P Statement
Avoid breathing dust/fume/gas/mist/vapors/spray.
IF ON SKIN: Wash with plenty of soap and water.
Wear protective gloves/protective clothing/eye protection/face protection.
IF IN EYES: Rinse cautiously with water for

GHS Signal Word: Warning

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Product Certifications
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RUO – Research Use Only