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CHAPS, 98%, Thermo Scientific Chemicals

Catalog No. p-4228496
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Quantity:
5 g
25 g
100 g
Packaging:
Glass bottle
Catalog No. Quantity Packaging
AC436550050 5 g Glass bottle
AC436550250 25 g Glass bottle
AC436551000 100 g Glass bottle
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Catalog No. AC436550050

Supplier: Thermo Scientific Chemicals 436550050

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Description

CHAPS, 3-[(3-cholamidopropyl)dimethylammonio]-1-propanesulfonate, CAS # 75621-03-3, is a non-denaturing zwitterionic detergent that can be used for solubilizing membrane proteins.

This Thermo Scientific Chemicals brand product was originally part of the Acros Organics product portfolio. Some documentation and label information may refer to the legacy brand. The original Acros Organics product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

General Description

  • CHAPS (3-((3-cholamidopropyl) dimethylammonio)-1-propanesulfonate) is a zwitterionic non-denaturing detergent
  • It is suitable for applications which require protection of native protein conformation

Applications

  • CHAPS can be used for the solubilization and purification of membrane proteins
  • It is also used in conjunction with nonionic detergents like Triton X-100
  • It can be used as a non-denaturing zwitterionic detergent for the study of membrane chemistry

Chemical Identifiers

CAS 75621-03-3
Molecular Formula C32H58N2O7S
Molecular Weight (g/mol) 614.9
MDL Number MFCD00012116
InChI Key UMCMPZBLKLEWAF-GBSSQDIOSA-N
Synonym 3-[(3-Cholamidopropyl)dimethylammonio]-1-propanesulfonate
PubChem CID 134129639
IUPAC Name 3-[dimethyl-[3-[[(4R)-4-[(3R,5S,7R,8R,9R,10S,12S,13R,14R,17S)-3,7,12-trihydroxy-10,13-dimethyl-2,3,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl]pentanoyl]amino]propyl]azaniumyl]propane-1-sulfonate
SMILES CC(CCC(=O)NCCC[N+](C)(C)CCCS(=O)(=O)[O-])C1CCC2C1(C(CC3C2C(CC4C3(CCC(C4)O)C)O)O)C

Specifications

Melting Point 267.2°C to 271.4°C
Color White
Elemental Analysis 4.46 to 4.65 % N
Infrared Spectrum Authentic
Assay Percent Range 98%
Packaging Glass bottle
Quantity 5 g
Merck Index 15,2043
Solubility Information Solubility in water: soluble. Other solubilities: soluble in alcohols like methanol and ethanol
Formula Weight 614.9
Percent Purity 98%
Physical Form Crystalline Powder
Chemical Name or Material CHAPS
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Safety and Handling

Hazard Category GHS Signal Word: Warning
Hazard Statement GHS H Statement
Causes skin irritation.
Causes serious eye irritation.
May cause respiratory irritation.
Precautionary Statement GHS P Statement
Avoid breathing dust/fume/gas/mist/vapors/spray.
IF ON SKIN: Wash with plenty of soap and water.
Wear protective gloves/protective clothing/eye protection/face protection.
IF IN EYES: Rinse cautiously with water for

RUO – Research Use Only