Antibodies
Antibodies are glycoproteins that serve an essential role in the immune system to protects animals from infection, or the cytotoxic effects of foreign compounds, by binding with high affinity to invasive molecules; classified as primary or secondary.
Primary Antibodies
(210,524)
Secondary Antibodies
(3,150)
Isotype Controls and Standards
(640)
Antibody Panels and Kits
(60)
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Invitrogen™ PF4V1 Polyclonal Antibody
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Rabbit Polyclonal Antibody
| Applications | Immunohistochemistry,Western Blot,Immunocytochemistry |
|---|---|
| Type de produit | Antibody |
| Conjugué | Unconjugated |
| Espèces cibles | Human |
| Concentration | 0.5 mg/mL |
| Primaire ou secondaire | Primary |
| Forme | Liquid |
| Contenu et stockage | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| État réglementaire | RUO |
| Numéro d’ordre du gène | P10720 |
| Immunogène | Recombinant Platelet Factor 4 Variant 1 (PF4V1) (Met1-Ser104). |
| Expression | PF4V1 |
| Classification | Polyclonal |
| Identification génétique (Entrez) | 5197 |
| Méthode de purification | Protein A |
| Espèces hôtes | Rabbit |
| Symboles de gène(s) | PF4V1 |
| Formule | PBS with 50% glycerol and 0.05% ProClin 300; pH 7.4 |
| Alias de gène | C-X-C motif chemokine 4; C-X-C motif chemokine 4 variant; CXCL4L1; CXCL4V1; PF4A; PF4alt; PF4-ALT; PF4V1; PF4var1; platelet factor 4 variant; platelet factor 4 variant 1; Platelet factor 4 variant(4-74); Platelet factor 4 variant(5-74); Platelet factor 4 variant(6-74); platelet factor 4, variant 1 (PF4-like); SCYB4V1 |
| Antigène | PF4V1 |
Invitrogen™ CD127 Monoclonal Antibody (eBioRDR5), Brilliant Ultra Violet™ 805, eBioscience™
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Mouse Monoclonal Antibody
| Applications | Flow Cytometry |
|---|---|
| Type de produit | Antibody |
| Isotype | IgG1 κ |
| Conjugué | Brilliant Ultraviolet 805 |
| Espèces cibles | Human |
| Concentration | 5 μL/Test |
| Primaire ou secondaire | Primary |
| Forme | Liquid |
| Contenu et stockage | 4°C, store in dark, DO NOT FREEZE! |
| État réglementaire | RUO |
| Numéro d’ordre du gène | P16871 |
| Expression | Il7r |
| Classification | Monoclonal |
| Identification génétique (Entrez) | 3575 |
| Méthode de purification | Affinity chromatography |
| Espèces hôtes | Mouse |
| Symboles de gène(s) | Il7r |
| Formule | PBS with BSA and 0.09% sodium azide; pH 7.2 |
| Alias de gène | CD127; CD127 antigen; CDW127; IL 7 receptor; IL 7R a; IL 7R subunit alpha; IL 7R α; IL 7Ra; IL 7Rα; IL7 receptor; IL-7 receptor alpha chain; IL7 receptor subunit alpha; IL-7 receptor subunit alpha; IL7R; IL-7R; IL7R a; IL7R alpha; IL7R subunit alpha; IL-7R subunit alpha; IL7R α; IL7RA; IL-7RA; IL-7Ralpha; IL-7R-alpha; IL7Rα; ILRA; interleukin 7 receptor; interleukin 7 receptor alpha chain; interleukin 7 receptor isoform H5-6; Interleukin7 receptor subunit alpha; interleukin-7 receptor subunit alpha; MGC107557; sCD127; soluble IL 7 receptor; soluble IL 7R |
| Clone | eBioRDR5 |
| Antigène | CD127 |
| Applications | Western Blot |
|---|---|
| Type de produit | Antibody |
| Isotype | IgG1 |
| Conjugué | Unconjugated |
| Espèces cibles | Human |
| Concentration | 1 mg/mL |
| Primaire ou secondaire | Primary |
| Contenu et stockage | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Forme | Liquid |
| État réglementaire | RUO |
| Numéro d’ordre du gène | Q99683 |
| Immunogène | Recombinant human MAP3K5 (immunogen range is 1191-1300). |
| Expression | MAP3K5 |
| Classification | Monoclonal |
| Identification génétique (Entrez) | 4217 |
| Méthode de purification | Protein A |
| Espèces hôtes | Mouse |
| Formule | PBS with 50% glycerol, 0.5% BSA and 0.09% sodium azide |
| Alias de gène | 7420452D20Rik; apoptosis signal regulating kinase 1; apoptosis signal-regulating kinase 1; ASK; ASK 1; ASK1; ASK-1; EC 2.7.11.25; kinase ASK1; M3K5; MAP/ERK kinase kinase 5; Map3k5; MAPK/ERK kinase kinase 5; MAPKKK5; MEK kinase 5; MEKK 5; Mekk5; mitogen activated protein kinase kinase kinase 5; mitogen-activated protein kinase kinase kinase 5; RGD1306565; RP3-325F22.4 |
| Clone | K52022_9A7 |
| Antigène | ASK1 |
Invitrogen™ CCL16 Polyclonal Antibody
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Rabbit Polyclonal Antibody
| Applications | Immunohistochemistry (Paraffin),Western Blot |
|---|---|
| Type de produit | Antibody |
| Isotype | IgG |
| Conjugué | Unconjugated |
| Espèces cibles | Human |
| Concentration | 0.5 mg/mL |
| Primaire ou secondaire | Primary |
| Forme | Liquid |
| Contenu et stockage | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| État réglementaire | RUO |
| Numéro d’ordre du gène | O15467 |
| Immunogène | Recombinant Chemokine C-C-Motif Ligand 16 (CCL16) (Ala20-Gln120). |
| Expression | CCL16 |
| Classification | Polyclonal |
| Identification génétique (Entrez) | 6360 |
| Méthode de purification | Protein A |
| Espèces hôtes | Rabbit |
| Symboles de gène(s) | CCL16 |
| Formule | PBS with 50% glycerol and 0.05% ProClin 300; pH 7.4 |
| Alias de gène | C-C motif chemokine 16; C-C motif chemokine ligand 16; CCL16; chemokine (C-C motif) ligand 16; Chemokine CC-4; Chemokine LEC; CKb12; HCC-4; IL-10-inducible chemokine; ILINCK; LCC-1; LEC; liver CC chemokine-1; liver-expressed chemokine; LMC; Lymphocyte and monocyte chemoattractant; MGC117051; monotactin-1; MTN-1; NCC4; NCC-4; new CC chemokine 4; SCYA16; SCYL4; small inducible cytokine subfamily A (Cys-Cys), member 16; small-inducible cytokine A16 |
| Antigène | CCL16 |
Invitrogen™ LRRK2 Recombinant Rabbit Monoclonal Antibody (HL3167)
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Rabbit Recombinant Monoclonal Antibody
| Applications | Immunohistochemistry (Frozen),Western Blot |
|---|---|
| Type de produit | Antibody |
| Isotype | IgG |
| Conjugué | Unconjugated |
| Espèces cibles | Human,Mouse |
| Concentration | 1 mg/mL |
| Primaire ou secondaire | Primary |
| Forme | Liquid |
| Contenu et stockage | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| État réglementaire | RUO |
| Numéro d’ordre du gène | Q5S006, Q5S007 |
| Immunogène | The immunogen used to generate this antibody corresponds to human LRRK2. |
| Expression | LRRK2 |
| Classification | Recombinant Monoclonal |
| Identification génétique (Entrez) | 120892, 66725 |
| Méthode de purification | Protein A |
| Espèces hôtes | Rabbit |
| Symboles de gène(s) | LRRK2 |
| Formule | PBS with no preservative |
| Alias de gène | 4921513O20Rik; 9330188B09Rik; augmented in rheumatoid arthritis 17; AURA17; AW561911; BC 300-268; cI-46; D630001M17Rik; DARDARIN; DKFZp434H2111; FLJ45829; Gm927; leucine rich repeat kinase 2; leucine-rich repeat kinase 2; leucine-rich repeat serine/threonine-protein kinase 2; LRR kinase 2; LRRK 2; Lrrk2; LRRK-2; PARK8; RIPK7; ROCO2 |
| Clone | HL3167 |
| Antigène | LRRK2 |
| Applications | Western Blot |
|---|---|
| Type de produit | Antibody |
| Isotype | IgG1 |
| Conjugué | Unconjugated |
| Espèces cibles | Human |
| Concentration | 1 mg/mL |
| Primaire ou secondaire | Primary |
| Contenu et stockage | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Forme | Liquid |
| État réglementaire | RUO |
| Numéro d’ordre du gène | P35638 |
| Immunogène | Recombinant human DDIT3 (immunogen range is 1-169). |
| Expression | DDIT3 |
| Classification | Monoclonal |
| Identification génétique (Entrez) | 1649 |
| Méthode de purification | Protein A |
| Espèces hôtes | Mouse |
| Formule | PBS with 50% glycerol, 0.5% BSA and 0.09% sodium azide |
| Alias de gène | C/EBP homologous protein; C/EBP homoologous protein 10; C/EBP zeta; C/EBP-homologous protein; C/EBP-homologous protein 10; CCAAT/enhancer-binding protein homologous protein; CEBPZ; CHOP; CHOP10; CHOP-10; Ddit3; DDIT-3; ddit3.L; DNA damage inducible transcript 3; DNA damage inducible transcript 3 L homeolog; DNA damage-inducible transcript 3 protein; DNA-damage inducible transcript 3; DNA-damage-inducible transcript 3; GADD153; growth arrest and DNA damage-inducible; growth arrest and DNA damage-inducible protein GADD153; Growth arrest and DNA-damage-inducible protein GADD153; MGC4154; transcription factor GADD153; Xchop; XELAEV_18013440mg |
| Clone | K49008_7F7 |
| Antigène | CHOP |
Invitrogen™ mTOR Monoclonal Antibody (D7)
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Mouse Monoclonal Antibody
| Applications | Immunohistochemistry (Paraffin),Western Blot |
|---|---|
| Type de produit | Antibody |
| Isotype | IgG2b κ |
| Conjugué | Unconjugated |
| Espèces cibles | Human,Rat,Pig |
| Concentration | 1 mg/mL |
| Primaire ou secondaire | Primary |
| Forme | Liquid |
| Contenu et stockage | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| État réglementaire | RUO |
| Numéro d’ordre du gène | P42345, P42346 |
| Immunogène | Recombinant Serine/threonine-protein kinase mTOR (mTOR) (Ala2226-Val2488). |
| Expression | MTOR |
| Classification | Monoclonal |
| Identification génétique (Entrez) | 100127359, 2475, 56718 |
| Méthode de purification | Protein A/G |
| Espèces hôtes | Mouse |
| Symboles de gène(s) | MTOR |
| Formule | PBS with 50% glycerol and 0.05% ProClin 300; pH 7.4 |
| Alias de gène | 2610315D21Rik; AI327068; angiopoietin-like factor CDT6; FK506 binding protein 12-rapamycin associated protein 1; FK506 binding protein 12-rapamycin associated protein 2; FK506-binding protein 12-rapamycin complex-associated protein 1; FKBP12-rapamycin complex-associated protein; FKBP12-rapamycin complex-associated protein 1; FKBP-rapamycin associated protein; FKBP-rapamycin associated protein (FRAP); FKBP-rapamycin-associated protein FRAP; flat; FRAP; FRAP1; FRAP2; Mammalian target of rapamycin; mechanistic target of rapamycin; mechanistic target of rapamycin (serine/threonine kinase); mechanistic target of rapamycin kinase; Mtor; m-TOR; mTORC1; Raft1; Rapamycin and FKBP12 target 1; rapamycin and FKBP12 target-1 protein; rapamycin associated protein FRAP2; rapamycin target protein 1; RAPT1; serine/threonine-protein kinase mTOR; SKS |
| Clone | D7 |
| Antigène | mTOR |
Invitrogen™ FSTL1 Monoclonal Antibody (C7)
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Mouse Monoclonal Antibody
| Applications | Immunohistochemistry (Paraffin),Western Blot,Immunocytochemistry |
|---|---|
| Type de produit | Antibody |
| Isotype | IgG1 κ |
| Conjugué | Unconjugated |
| Espèces cibles | Human,Pig |
| Concentration | 1 mg/mL |
| Primaire ou secondaire | Primary |
| Forme | Liquid |
| Contenu et stockage | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| État réglementaire | RUO |
| Numéro d’ordre du gène | Q12841 |
| Immunogène | Recombinant Follistatin Like Protein 1 (FSTL1) (Glu21-Ile308). |
| Expression | Fstl1 |
| Classification | Monoclonal |
| Identification génétique (Entrez) | 110256417, 11167 |
| Méthode de purification | Protein A/G |
| Espèces hôtes | Mouse |
| Symboles de gène(s) | Fstl1 |
| Formule | PBS with 50% glycerol and 0.05% ProClin 300; pH 7.4 |
| Alias de gène | AI316791; AW107808; FLJ50214; FLJ52277; follistatin like 1; follistatin-like 1; follistatin-like protein 1; Follistatin-related protein 1; FRP; FSL1; Fstl; FSTL1; MIR198; OCC1; OCC-1; TGF-beta-inducible protein TSC-36; tsc36; TSC-36 |
| Clone | C7 |
| Antigène | FSTL1 |
Invitrogen™ ENPP5 Recombinant Rabbit Monoclonal Antibody (23GB5700)
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Rabbit Recombinant Monoclonal Antibody
| Applications | Flow Cytometry,Western Blot,Immunocytochemistry |
|---|---|
| Type de produit | Antibody |
| Isotype | IgG |
| Conjugué | Unconjugated |
| Espèces cibles | Human,Mouse,Rat |
| Primaire ou secondaire | Primary |
| Forme | Liquid |
| Contenu et stockage | -20°C |
| État réglementaire | RUO |
| Numéro d’ordre du gène | P84039, Q9EQG7, Q9UJA9 |
| Immunogène | A synthesized peptide derived from human ENPP5 (400-477AA). |
| Expression | ENPP5 |
| Classification | Recombinant Monoclonal |
| Identification génétique (Entrez) | 316249, 59084, 83965 |
| Méthode de purification | Affinity chromatography |
| Espèces hôtes | Rabbit |
| Symboles de gène(s) | ENPP5 |
| Formule | PBS with 50% glycerol and 0.02% sodium azide; pH 7.4 |
| Alias de gène | AW061004; D17Abb1e; EC 3.1; ectonucleotide pyrophosphatase/phosphodiesterase 5; ectonucleotide pyrophosphatase/phosphodiesterase 5 (putative); ectonucleotide pyrophosphatase/phosphodiesterase family member 5; E-NPP 5; ENPP5; E-NPP5; KIAA0879; mKIAA4152; Npp5; NPP-5; UNQ550/PRO1107 |
| Clone | 23GB5700 |
| Antigène | ENPP5 |
Invitrogen™ F(ab)-Goat anti-Rabbit IgG Fc Secondary Antibody, Alexa Fluor™ 568
F(ab)-Goat Polyclonal Secondary Antibody
| Applications | Peptide Array,Flow Cytometry,Immunohistochemistry (Paraffin),Immunohistochemistry (PFA fixed),Western Blot,Immunocytochemistry |
|---|---|
| Type de produit | Secondary Antibody |
| Isotype | IgG F(ab) |
| Conjugué | Alexa Fluor 568 |
| Espèces cibles | Rabbit |
| Concentration | 0.2 mg/mL |
| Primaire ou secondaire | Secondary |
| Forme | Liquid |
| Contenu et stockage | 4°C, store in dark, DO NOT FREEZE! |
| État réglementaire | RUO |
| Immunogène | Rabbit IgG Fc. |
| Classification | Polyclonal |
| Méthode de purification | Size-exclusion chromatography |
| Espèces hôtes | Goat |
| Formule | PBS with 5mM sodium azide; pH 7.5 |
| Antigène | Rabbit IgG Fc |
Invitrogen™ CD47 Chimeric Recombinant Rabbit Monoclonal Antibody (B6H12)
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Rabbit Recombinant Monoclonal Antibody
| Applications | ELISA,Flow Cytometry,Inhibition Assays,Western Blot,Immunocytochemistry |
|---|---|
| Type de produit | Antibody |
| Isotype | IgG κ |
| Conjugué | Unconjugated |
| Espèces cibles | Human |
| Concentration | 1 mg/mL |
| Primaire ou secondaire | Primary |
| Forme | Liquid |
| Contenu et stockage | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| État réglementaire | RUO |
| Numéro d’ordre du gène | Q08722 |
| Immunogène | The original antibody was generated by immunizing BALB/c mice with purified placental RGD-binding proteins (PRBP). |
| Expression | CD47 |
| Classification | Recombinant Monoclonal |
| Identification génétique (Entrez) | 961 |
| Méthode de purification | Protein A |
| Espèces hôtes | Rabbit |
| Symboles de gène(s) | CD47 |
| Formule | PBS with 0.02% ProClin 300 |
| Alias de gène | 9130415E20Rik; AA407862; AI848868; antigen identified by monoclonal antibody 1D8; antigenic surface determinant protein OA3; AW108519; B430305P08Rik; Cd47; CD47 antigen; CD47 antigen (Rh-related antigen, integrin-associated signal transducer); CD47 antigen/integrin-associated protein; CD47 glycoprotein; CD47 molecule; CD47/IAP; IAP; integrin associated protein; integrin-associated protein; integrin-associated signal transducer; Itgp; Leukocyte surface antigen CD47; MER6; OA3; Protein MER6; Rh-related antigen; sCD47; soluble CD 47; soluble CD47 |
| Clone | B6H12 |
| Antigène | CD47 Chimeric |
Invitrogen™ Caspase 6 Monoclonal Antibody (D4)
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Mouse Monoclonal Antibody
| Applications | Immunohistochemistry,Western Blot,Immunocytochemistry |
|---|---|
| Type de produit | Antibody |
| Conjugué | Unconjugated |
| Espèces cibles | Human,Rat |
| Concentration | 1 mg/mL |
| Primaire ou secondaire | Primary |
| Forme | Liquid |
| Contenu et stockage | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| État réglementaire | RUO |
| Numéro d’ordre du gène | O35397, P55212 |
| Immunogène | Recombinant Caspase 6 (CASP6) (Ala194-Asn293). |
| Expression | Casp6 |
| Classification | Monoclonal |
| Identification génétique (Entrez) | 83584, 839 |
| Méthode de purification | Protein A/G |
| Espèces hôtes | Mouse |
| Symboles de gène(s) | Casp6 |
| Formule | PBS with 50% glycerol and 0.05% ProClin 300; pH 7.4 |
| Alias de gène | apoptotic protease MCH-2; CASP6; CASP-6; caspase 6; caspase 6, apoptosis-related cysteine peptidase; caspase 6, apoptosis-related cysteine protease; caspase-6; Caspase-6 subunit p11; Caspase-6 subunit p18; mCASP-6; MCH2 |
| Clone | D4 |
| Antigène | Caspase 6 |
Invitrogen™ Defensin 5 Polyclonal Antibody
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Rabbit Polyclonal Antibody
| Applications | Immunohistochemistry,Western Blot |
|---|---|
| Type de produit | Antibody |
| Conjugué | Unconjugated |
| Espèces cibles | Human |
| Concentration | 0.5 mg/mL |
| Primaire ou secondaire | Primary |
| Forme | Liquid |
| Contenu et stockage | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| État réglementaire | RUO |
| Numéro d’ordre du gène | Q01523 |
| Immunogène | Recombinant Defensin Alpha 5, Paneth Cell Specific (DEFa5) (Glu20-Arg94). |
| Expression | DEFA5 |
| Classification | Polyclonal |
| Identification génétique (Entrez) | 1670 |
| Méthode de purification | Protein A |
| Espèces hôtes | Rabbit |
| Symboles de gène(s) | DEFA5 |
| Formule | PBS with 50% glycerol and 0.05% ProClin 300; pH 7.4 |
| Alias de gène | DEF5; DEFA5; defensin 5; defensin alpha 5; Defensin, alpha 5; defensin, alpha 5, Paneth cell-specific; defensin, alpha 5, preproprotein; defensin-5; HD5; HD-5; HD5(20-94); HD5(23-94); HD5(29-94); HD5(56-94); HD5(63-94); MGC129728 |
| Antigène | Defensin 5 |
Invitrogen™ CD23 Monoclonal Antibody (EBVCS2), NovaFluor™ Yellow 755, eBioscience™
Mouse Monoclonal Antibody
| Applications | Flow Cytometry |
|---|---|
| Type de produit | Antibody |
| Isotype | IgG1 κ |
| Conjugué | NovaFluor Yellow 755 |
| Espèces cibles | Human |
| Concentration | 0.4 μg/Test |
| Primaire ou secondaire | Primary |
| Forme | Liquid |
| Contenu et stockage | 4°C, store in dark, DO NOT FREEZE! |
| État réglementaire | RUO |
| Numéro d’ordre du gène | P06734 |
| Expression | FCER2 |
| Classification | Monoclonal |
| Identification génétique (Entrez) | 2208 |
| Méthode de purification | Affinity chromatography |
| Espèces hôtes | Mouse |
| Symboles de gène(s) | FCER2 |
| Formule | PBS with BSA and 0.09% sodium azide; pH 7.2 |
| Alias de gène | BLAST-2; CD23; CD23 antigen; CD23A; CLEC4J; C-type lectin domain family 4 member J; C-type lectin domain family 4, member J; Fc epsilon receptor II; FC epsilon RII; Fc fragment of IgE receptor II; Fc fragment of IgE, low affinity II, receptor for (CD23); Fc receptor alpha multiple ligand receptor; Fc receptor, IgE, low affinity II, alpha polypeptide; Fcalpha muR; Fcalpha RII; Fce2; fc-epsilon-RII; FCER2; Fcer2a; FceRII; IGEBF; Immunoglobulin E-binding factor; immunoglobulin epsilon-chain; low affinity immunoglobulin epsilon Fc receptor; Low affinity immunoglobulin epsilon Fc receptor membrane-bound form; Low affinity immunoglobulin epsilon Fc receptor soluble form; low-affinity IgE receptor; Ly-42; lymphocyte IgE receptor |
| Clone | EBVCS2 |
| Antigène | CD23 |
Invitrogen™ LKB1 Recombinant Rabbit Monoclonal Antibody (PSH09-29)
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Rabbit Recombinant Monoclonal Antibody
| Applications | Immunohistochemistry (Paraffin),Immunoprecipitation,Western Blot |
|---|---|
| Type de produit | Antibody |
| Isotype | IgG |
| Conjugué | Unconjugated |
| Espèces cibles | Human,Mouse,Rat |
| Concentration | 1 mg/mL |
| Primaire ou secondaire | Primary |
| Forme | Liquid |
| Contenu et stockage | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| État réglementaire | RUO |
| Numéro d’ordre du gène | D4AE59, Q15831, Q9WTK7 |
| Immunogène | Recombinant protein within human LKB1 aa 1-400. |
| Expression | STK11 |
| Classification | Recombinant Monoclonal |
| Identification génétique (Entrez) | 20869, 314621, 6794 |
| Méthode de purification | Protein A |
| Espèces hôtes | Rabbit |
| Symboles de gène(s) | STK11 |
| Formule | PBS with 0.1% BSA, 40% glycerol and 0.05% sodium azide; pH 7.4 |
| Alias de gène | AA408040; CAMK group; CAMKL family; hLKB1; liver kinase B1; Liver kinase B1 homolog; LKB 1; LKB1; LKB-1; LKB1(S); Par-4; PJS; polarization-related protein LKB1; R75140; renal carcinoma antigen NY-REN-19; serine/threonine kinase 11; serine/threonine-protein kinase 11; serine/threonine-protein kinase LKB1; serine/threonine-protein kinase STK11; STK11 |
| Clone | PSH09-29 |
| Antigène | LKB1 |