Cell Lysis Detergents
MilliporeSigma™ Digitonin Solution- high purity
Has been used to solubilize receptors and permeabilize membranes for sample prep and analysis
Thermo Scientific™ Brij™-35, 30% Solution
Stabilized Brij-35 detergent provided as 10% and 30% solutions for use in various protein methods including cell lysis and HPLC.
Gibco™ CTS™ AAV-MAX Lysis Buffer
Gibco CTS AAV-MAX Lysis Buffer is a ready-to-use cell lysis reagent for the extraction of adeno-associated virus (AAV) particles from producer HEK293 cells.
MilliporeSigma™ CHAPS, Molecular biology grade, Calbiochem™,
CAS: 75621-03-3
MilliporeSigma™ ELUGENT™ Detergent, 50% Solution, Calbiochem™,
CAS: 132778-08-6
MilliporeSigma™ TWEEN™ 80, Protein Grade™ Detergent, 10% Solution, Sterile-Filtered, Calbiochem™,
CAS: 9005-65-6 Molecular Formula: (C2H4O)x(C2H4O)z(C2H4O)y(C2H4O)wC24H44O6 Molecular Weight (g/mol): 604.82 MDL Number: MFCD00082107 InChI Key: HDTIFOGXOGLRCB-KTKRTIGZNA-N Synonym: Polysorbate 80 IUPAC Name: 2-{2-[3,5-bis(2-hydroxyethoxy)oxolan-2-yl]-2-(2-hydroxyethoxy)ethoxy}ethyl (9E)-octadec-9-enoate SMILES: CCCCCCCC\C=C/CCCCCCCC(=O)OCCOCC(OCCO)C1OCC(OCCO)C1OCCO
Thermo Scientific™ Sodium Deoxycholate Detergent
Water-soluble, ionic detergent used in cell lysis buffers (e.g., RIPA buffer) to disrupt protein interactions for liposome and membrane protein isolation.
Thermo Scientific™ High-Purity Maltoside Detergents
Maltoside detergents are a class of nonionic surfactants that are commonly utilized in the field of membrane protein solubilization. Several studies have shown that these surfactants are highly effective in extracting and stabilizing membrane proteins.
Gibco™ AAV-MAX Lysis Buffer
AAV-MAX Lysis Buffer is a ready-to-use cell lysis reagent for the extraction of adeno-associated virus (AAV) particles from producer HEK293 cells. Cell lysis is detergent-based, eliminating the need for mechanical cell disruption.
MilliporeSigma™ Triton X-100 Detergent, Molecular biology grade, Calbiochem™,
CAS: 9002-93-1 Molecular Formula: C16H26O2 Molecular Weight (g/mol): 250.38 MDL Number: MFCD00132505 InChI Key: JYCQQPHGFMYQCF-UHFFFAOYSA-N Synonym: Polyethylene Glycol-p-isooctylphenyl Ether PubChem CID: 5590 IUPAC Name: 2-[4-(2,4,4-trimethylpentan-2-yl)phenoxy]ethan-1-ol SMILES: CC(C)(C)CC(C)(C)C1=CC=C(OCCO)C=C1
MilliporeSigma™ HECAMEG™, Calbiochem™,
Molecular Formula: C15H29NO7 Molecular Weight (g/mol): 335.4 MDL Number: MFCD00077425 InChI Key: XPIVOYOQXKNYHA-RGDJUOJXSA-N Synonym: Methyl-6-O-(N-heptylcarbamoyl)-α-D-glucopyranoside PubChem CID: 2733955 IUPAC Name: [(2R,3S,4S,5R,6S)-3,4,5-trihydroxy-6-methoxyoxan-2-yl]methyl N-heptylcarbamate SMILES: CCCCCCCNC(=O)OC[C@H]1O[C@H](OC)[C@H](O)[C@@H](O)[C@@H]1O
MilliporeSigma™ TWEEN™ 20 Detergent, Calbiochem™,
CAS: 9005-64-5 Molecular Formula: (C2H4O)y(C2H4O)w(C2H4O)x(C2H4O)zC18H34O6 Molecular Weight (g/mol): 522.68 MDL Number: MFCD00165986 InChI Key: HMFKFHLTUCJZJO-UHFFFAOYNA-N Synonym: Polysorbate 20 PubChem CID: 443314 IUPAC Name: 2-{2-[3,4-bis(2-hydroxyethoxy)oxolan-2-yl]-2-(2-hydroxyethoxy)ethoxy}ethyl dodecanoate SMILES: CCCCCCCCCCCC(=O)OCCOCC(OCCO)C1OCC(OCCO)C1OCCO
MilliporeSigma™ DDMAB, ≥98%, Calbiochem™,
Molecular Formula: C18H37NO2 Molecular Weight (g/mol): 299.499 InChI Key: ZFVNBVQBIZJUEY-UHFFFAOYSA-N Synonym: N-Dodecyl-N,N-(dimethylammonio)butyrate PubChem CID: 11536737 IUPAC Name: 4-[dodecyl(dimethyl)azaniumyl]butanoate SMILES: CCCCCCCCCCCC[N+](C)(C)CCCC(=O)[O-]